I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists.
Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
(89)zr-GC1008 PET imaging and GC1008 treatment of recurrent glioma patients.
Published in: Journal of Clinical Oncology
Martha W. den Hollander,
Frederike Bensch,
Andor W. J. M. Glaudemans,
Roelien H. Enting, Sophie Bunskoek,
Thijs H. Oude Munnink,
Marjolijn N. Lub-de Hooge, Joseph Pearlberg,
Jourik A. Gietema,
Liesbeth de Vries,
Annemiek M. E. Walenkamp
Value of C-11-methionine PET in imaging brain tumours and metastases
Published in: European Journal of Nuclear Medicine and Molecular Imaging
C-11-methionine (MET) is the most popular amino acid tracer used in PET imaging of brain tumours. Because of its characteristics, MET PET provides a high detection rate of brain tumours and good lesion delineation. This review focuses on the role of MET PET in imaging cerebral gliomas. The Introduction provides a clinical overview of what is important in primary brain tumours, recurrent brain tumours and brain metastases. The indications for radiotherapy and the results and problems arising after chemoradiotherapy in relation to imaging (pseudoprogression or radionecrosis) are discussed....
Nuclear medicine imaging of inflammatory diseases
A 45-yr-old woman with recurrent thromboembolic events and increased 18F-FDG uptake
The Use of F-18-FDG-PET/CT for Diagnosis and Treatment Monitoring of Inflammatory and Infectious Diseases
Published in: Clinical & Developmental Immunology
FDG-PET, combined with CT, is nowadays getting more and more relevant for the diagnosis of several infectious and inflammatory diseases and particularly for therapy monitoring. Thus, this paper gives special attention to the role of FDG-PET/CT in the diagnosis and therapy monitoring of infectious and inflammatory diseases. Enough evidence in the literature already exists about the usefulness of FDG-PET/CT in the diagnosis, management, and followup of patients with sarcoidosis, spondylodiscitis, and vasculitis. For other diseases, such as inflammatory bowel diseases, rheumatoid arthritis, autoimmune pancreatitis, and fungal infections, hard...
