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Andor Glaudemans
prof. dr.

I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.

11C-Methionine uptake in meningiomas after stereotactic radiotherapy.
OBJECTIVE: 11C-Methionine positron emission tomography (MET-PET) is used for stereotactic radiotherapy planning in meningioma patients. The role of MET-PET during subsequent follow-up (FU) is unclear. We analyzed the uptake of 11C-Methionine before and after stereotactic radiotherapy (SRT) in patients with a complex meningioma and investigated if there was a difference between patients with progressive disease (PD) and stable disease (SD) during FU. METHODS: This retrospective study investigates 62 MET-PETs in 29 complex meningioma patients. Standardized uptake value (SUV) max and SUV peak tumor-to-normal ratios (T/N-ratios) were calculated, comparing...
Nuclear medicine practice for the assessment of cardiac sarcoidosis and amyloidosis: A survey endorsed by the EANM and EACVI
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Irene Gotuzzo, Riemer H J A Slart, Alessia Gimelli, Nabila Ashri, Constantinos Anagnostopoulos, Jan Bucerius, Ronny R Buechel, Oliver Gaemperli, Olivier Gheysens, Andor W J M Glaudemans, Gilbert Habib, Fabian Hyafil, Mark Lubberink, Antti Saraste, Tomaz Podlesnikar, Marc R Dweck, Paola A Erba
EANM consensus document on the use of [18F]FDG PET/CT in fever and inflammation of unknown origin
Published in: European Journal of Nuclear Medicine and Molecular Imaging
PURPOSE: Patients with fever and inflammation of unknown origin (FUO/IUO) are clinically challenging due to variable clinical presentations with nonspecific symptoms and many differential diagnoses. Positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[ 18F]fluoro-D-glucose ([ 18F]FDG) is increasingly used in FUO and IUO, but the optimal diagnostic strategy remains controversial. This consensus document aims to assist clinicians and nuclear medicine specialists in the appropriate use of [ 18F]FDG-PET/CT in FUO and IUO based on current evidence. METHODS: A working group created by the EANM infection and inflammation committee performed...
Søren Hess, Edel Noriega-Álvarez, Lucia Leccisotti, Giorgio Treglia, Domenico Albano, Anne Roivainen, Andor W J M Glaudemans, Olivier Gheysens
Multimodality imaging to assess diagnosis and evaluate complications of large vessel arteritis
Published in: Journal of Nuclear Cardiology
Different types of vasculitis can be distinguished according to the blood vessel’s size that is preferentially affected: large-vessel, medium-vessel, and small-vessel vasculitides. Giant cell arteritis (GCA) and Takayasu’s arteritis (TAK) are the main forms of large-vessel vasculitis, and may lead to lumen narrowing. Clinical manifestations of arterial narrowing on the short- and long term include vision loss, stroke, limb ischaemia and heart failure. Imaging tools are well established diagnostic tests for large-vessel vasculitis and may aid therapy monitoring in selected cases, while providing important information regarding the occurrence...
Ayaz Aghayev, Britanny Weber, Tiago Lins de Carvalho, Andor W J M Glaudemans, Pieter H Nienhuis, Kornelis S M van der Geest, Riemer H J A Slart
[18F]FDG PET/CT imaging of spinal infections
Published in: Clinical and Translational Imaging
The annual incidence of spinal infections has been rising significantly over the last years and is expected to increase even further. Spinal infections may include infection of the vertebral body and intervertebral disc (spondylodiscitis), paravertebral abscess, epidural abscess and septic arthritis of the facet joints. Positron emission tomography (PET) with [18F]FDG has high sensitivity for detecting spinal infections, may help in differentiating between spinal infection subtypes and is able to detect dissemination of infection outside the spine. [18F]FDG PET/CT is especially indicated if MRI is inconclusive, in patients...
Erik T. te Beek, Marc R.J. ten Broek, Sakar Abdul-Fatah, Andor W.J.M. Glaudemans