Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
[15O]H2O PET: Potential or Essential for Molecular Imaging?
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2023.08.002
document
Imaging water pathways in the human body provides an excellent way of measuring accurately the blood flow directed to different organs. This makes it a powerful diagnostic tool for a wide range of diseases that are related to perfusion and oxygenation. Although water PET has a long history, its true potential has not made it into regular clinical practice. The article highlights the potential of water PET in molecular imaging and suggests its prospective role in becoming an essential tool for the 21st century precision medicine in different...
Riemer H J A Slart, T Samara Martinez-Lucio, Hendrikus H Boersma, Ronald H Borra, Bart Cornelissen, Rudi A J O Dierckx, Magdalena Dobrolinska, Janine Doorduin, Paola A Erba, Andor W J M Glaudemans, Bruno Lima Giacobbo, Gert Luurtsema, Walter Noordzij, Joyce van Sluis, Charalampos Tsoumpas, Adriaan A Lammertsma
Long Versus Short Axial Field of View Immuno-PET/CT: Semiquantitative Evaluation for 89Zr-Trastuzumab
Published in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
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10.2967/jnumed.123.265621
The purpose of this study was to quantify any differences between the SUVs of 89Zr immuno-PET scans obtained using a PET/CT system with a long axial field of view (LAFOV; Biograph Vision Quadra) compared to a PET/CT system with a short axial field of view (SAFOV; Biograph Vision) and to evaluate how LAFOV PET scan duration affects image noise and SUV metrics. Methods: Five metastatic breast cancer patients were scanned consecutively on SAFOV and LAFOV PET/CT scanners. Four additional patients were scanned using only LAFOV PET/CT. Scans on...
Philipp Mohr, Joyce van Sluis, Laura Providência, Johannes H van Snick, Marjolijn N Lub-de Hooge, Antoon T Willemsen, Andor W J M Glaudemans, Ronald Boellaard, Adriaan A Lammertsma, Adrienne H Brouwers, Charalampos Tsoumpas
PET/MRI in practice: a clinical centre survey endorsed by the European Association of Nuclear Medicine (EANM) and the EANM Forschungs GmbH (EARL)
Published in: European Journal of Nuclear Medicine and Molecular Imaging
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10.1007/s00259-023-06308-y
Niek H.J. Prakken, Florent L. Besson, Ronald J.H. Borra, Florian Büther, Ronny R. Buechel, Ciprian Catana, Arturo Chiti, Rudi A.J.O. Dierckx, Marc R. Dweck, Paola A. Erba, Andor W.J.M. Glaudemans, Lars C. Gormsen, Ivalina Hristova, Michel Koole, Thomas C. Kwee, Felix M. Mottaghy, Irene Polycarpou, Mathias Prokop, Lars Stegger, Charalampos TsoumpasRiemer H.J.A. Slart
Variability of [18F]FDG-PET/LDCT reporting in vascular graft and endograft infection
Published in: European Journal of Nuclear Medicine and Molecular Imaging
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10.1007/s00259-023-06349-3
document
PURPOSE: 18F-fluoro-D-deoxyglucose positron emission tomography with low dose and/or contrast enhanced computed tomography ([ 18F]FDG-PET/CT) scan reveals high sensitivity for the diagnosis of vascular graft and endograft infection (VGEI), but lower specificity. Reporting [ 18F]FDG-PET/CT scans of suspected VGEI is challenging, reader dependent, and reporting standards are lacking. The aim of this study was to evaluate variability of [ 18F]FDG-PET/low dose CT (LDCT) reporting of suspected VGEI using a proposed standard reporting format. METHODS: A retrospective cohort study was conducted including all patients with a suspected VGEI (according...
David J Liesker, Stijn Legtenberg, Paola A Erba, Andor W J M Glaudemans, Clark J Zeebregts, Jean-Paul P M De Vries, Nabil Chakfé, Ben R Saleem, Riemer H J A Slart
Importance of Blood Glucose Management Before 18F-FDG PET/CT in 322 Patients with Bacteremia of Unknown Origin
Published in: Journal of Nuclear Medicine
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10.2967/jnumed.122.264839
We investigated the effects of blood glucose levels on the performance of 18F-FDG PET/CT for detecting an infection focus in patients with bacteremia. Methods: A total of 322 consecutive patients with bacteremia who underwent 18F-FDG PET/CT between 2010 and 2021 were included. Logistic regression analysis was performed to evaluate the association between finding a true-positive infection focus on 18F-FDG PET/CT and blood glucose level, type of diabetes, and use of hypoglycemic medication. C-reactive protein, leukocyte count, duration of antibiotic treatment, and type of isolated bacteria were considered as...