I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists.
Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
EANM/SNMMI guideline/procedure standard for [ 18F]FDG hybrid PET use in infection and inflammation in adults v2.0.
Published in: European Journal of Nuclear Medicine and Molecular Imaging
INTRODUCTION: Hybrid [ 18F]FDG PET imaging is currently the method of choice for a wide variety of infectious and inflammatory disorders and was recently adopted in several clinical guidelines. A large amount of evidence-based articles, guidelines and appropriate use criteria have been published since the first version of this guideline in 2013. PURPOSE: To provide updated evidence-based information to assist physicians in recommending, performing and interpreting hybrid [ 18F]FDG PET examinations for infectious and inflammatory disorders in the adult population. METHODS: A systematic literature search of evidence-based articles...
Gad Abikhzer, Giorgio Treglia, Matthieu Pelletier-Galarneau, John Buscombe, Arturo Chiti, Elizabeth H Dibble,
Andor W J M Glaudemans, Christopher J Palestro, Mike Sathekge, Alberto Signore, Francois Jamar, Ora Israel, Olivier Gheysens
Long Axial Field of View PET/CT: Technical Aspects in Cardiovascular Diseases
Published in: Seminars in Nuclear Medicine
Positron emission tomography / computed tomography (PET/CT) plays a pivotal role in the assessment of cardiovascular diseases (CVD), particularly in the context of ischemic heart disease. Nevertheless, its application in other forms of CVD, such as infiltrative, infectious, or inflammatory conditions, remains limited. Recently, PET/CT systems with an extended axial field of view (LAFOV) have been developed, offering greater anatomical coverage and significantly enhanced PET sensitivity. These advancements enable head-to-pelvis imaging with a single bed position, and in systems with an axial field of view (FOV) of approximately...
Tonantzin Samara Martinez-Lucio, Oscar Isaac Mendoza-Ibañez,
Wanling Liu,
Samaneh Mostafapour,
Zekai Li,
Laura Providência, Giordana Salvi de Souza,
Philipp Mohr,
Magdalena M Dobrolinska,
Bram van Leer,
Hendrea S A Tingen,
Joyce van Sluis,
Charalampos Tsoumpas,
Andor W J M Glaudemans,
Klaas Pieter Koopmans,
Adriaan A Lammertsma,
Riemer H J A Slart
Fetal dose minimization: ultra-low dose long axial field of view (LAFOV) PET/CT imaging of a pregnant patient
Published in: European Journal of Nuclear Medicine and Molecular Imaging
A cutting-edge technology for the future of nuclear medicine
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Using machine learning to improve the diagnostic accuracy of the modified Duke/ESC 2015 criteria in patients with suspected prosthetic valve endocarditis: a proof of concept study
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Introduction: Prosthetic valve endocarditis (PVE) is a serious complication of prosthetic valve implantation, with an estimated yearly incidence of at least 0.4-1.0%. The Duke criteria and subsequent modifications have been developed as a diagnostic framework for infective endocarditis (IE) in clinical studies. However, their sensitivity and specificity are limited, especially for PVE. Furthermore, their most recent versions (ESC2015 and ESC2023) include advanced imaging modalities, e.g., cardiac CTA and [18F]FDG PET/CT as major criteria. However, despite these significant changes, the weighing system using major and minor criteria has remained...
D. ten Hove,
R. H.J.A. Slart,
A. W.J.M. Glaudemans,
D. F. Postma,
A. Gomes, L. E. Swart, W. Tanis, P. P. van Geel,
G. Mecozzi, R. P.J. Budde, K. Mouridsen,
B. Sinha