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Andor Glaudemans
prof. dr.

I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.

Diagnostic Value of Increased [18F]FDG Uptake in Locoregional Lymph Nodes on PET/CT in Patients with Suspected Fracture-Related Infection
Published in: Diagnostics
Access to document 10.3390/diagnostics15050616 document
Background: Diagnosing fracture-related infection (FRI) without clinical confirmatory signs is challenging. [18F]FDG-PET/CT has been shown to have good diagnostic accuracy. However, direct interpretation criteria are lacking. The aim of this study was to assess the diagnostic value of increased FDG-uptake in locoregional lymph nodes on [18F]FDG-PET/CT in patients with suspected upper and lower extremity FRI. Methods: This was a retrospective cohort study of patients who underwent [18F]FDG-PET/CT for suspected extremity FRI in two tertiary referral centers between January 2011 and December 2023. The sensitivity, specificity and diagnostic value...
Paul Bosch, Andor W J M Glaudemans, Jean-Paul P M de Vries, Johannes H van Snick, Justin V C Lemans, Janna van den Kieboom, Monique G G Hobbelink, Geertje A M Govaert, Frank F A IJpma
Increased individual workload for nuclear medicine physicians over the past years: 2008-2023 data from The Netherlands
Published in: Annals of Nuclear Medicine
Access to document 10.1007/s12149-024-01995-5 document
OBJECIVE: To investigate temporal trends in the individual workload of nuclear medicine physicians at a large tertiary care academic center between 2008 and 2023. METHODS: This study analyzed the reporting workload of nuclear medicine physicians in a large tertiary care academic center in The Netherlands on 36 unique (randomly sampled) calendar days, for each year between 2008 and 2023. The average daily departmental workload (measured with relative value units) was calculated for each year between 2008 and 2023. The individual workload was calculated by dividing the average daily...
Asaad A H Amasha, Ömer Kasalak, Andor W J M Glaudemans, Walter Noordzij, Rudi A J O Dierckx, Klaas-Pieter Koopmans, Thomas C Kwee
Spondylodiscitis
Published in: The Quarterly Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.23736/S1824-4785.25.03619-2 document
Diagnosis of spondylodiscitis remains a challenge for clinicians. It results from various causative agents and conditions that can be challenging to identify. Prompt and appropriate treatment are necessary to prevent long-term irreversible complications and sequelae. The diagnosis of spondylodiscitis often constitutes a major challenge for the clinicians, and relies on the combination of clinical, laboratory and imaging findings. Various imaging techniques can be used for the workup of spondylodiscitis, with magnetic resonance imaging and 18-fluoro-deoxy-glucose positron emission tomography, combined with a CT being the most commonly used in...
Edel Noriega-Álvarez, Ringo Manta, Andor W Glaudemans, Olivier Gheysens, Virginia Peiró
Feasibility of the Absolute Quantification and Left Ventricular Segmentation of Cardiac Sympathetic Innervation in Wild-type Transthyretin Amyloidosis Cardiomyopathy with [123I]-MIBG SPECT/CT: the I-NERVE study.
Published in: Journal of Nuclear Cardiology
Access to document 10.1016/j.nuclcard.2025.102146 document
PURPOSE: Cardiac sympathetic neuronal dysfunction is an early marker in wild-type transthyretin amyloidosis cardiomyopathy (ATTRwt-CM). [ 123I]-MIBG imaging evaluates cardiac sympathetic innervation but lacks volumetric activity quantification in current methods. This study aims to quantify cardiac sympathetic neuronal dysfunction in ATTRwt-CM using [ 123I]-MIBG SPECT/CT and correlate findings with functional and structural cardiac parameters from echocardiogram and cardiac magnetic resonance imaging (CMR). METHODS: We conducted a single-center, descriptive, cross-sectional study to quantify absolute myocardial sympathetic function in ATTRwt-CM using [ 123I]-MIBG SPECT/CT. Retrospective reconstruction allowed for absolute tracer-uptake...
Alwin Tubben, Niek H J Prakken, Oleksandra V Ivashchenko, Hendrea S A Tingen, Andor W J M Glaudemans, Walter Noordzij, Hans L A Nienhuis, Peter van der Meer, Riemer H J A Slart
Intrapatient 16α-[18F]Fluoro-17β-Estradiol PET Heterogeneity as a Prognostic Factor for Endocrine Therapy Response and Survival in Patients with Estrogen Receptor-Positive Metastatic Breast Cancer.
Published in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Access to document 10.2967/jnumed.124.268984 document
Intrapatient heterogeneity of estrogen receptor (ER) expression on 16α-[ 18F]fluoro-17β-estradiol ([ 18F]FES) PET is related to outcome in patients with ER-positive metastatic breast cancer (MBC), but a validated and practical method to support clinical decision-making is lacking. Therefore, the [ 18F]FES PET heterogeneity score (i.e., percentage of [ 18F]FES-positive metastases) was validated as a prognostic factor for endocrine therapy response and survival in a large cohort of patients with newly diagnosed MBC. Furthermore, we explored 2 less laborious methods to predict the [ 18F]FES PET heterogeneity score. Methods:...
IMPACT-Metastatic Breast Consortium, Jasper J L van Geel, Jasmine Moustaquim, Jorianne Boers, Sjoerd G Elias, Esther M M Smeets, Jelijn J Knip, Andor W J M Glaudemans, Erik F J de Vries, Geke A P Hospers, Michel van Kruchten, Marcel Stokkel, Daniela E Oprea-Lager, Willemien C Menke-van der Houven van Oordt, Elisabeth G E de Vries, Carolina P Schröder