I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists.
Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Textural features of (18)F-fluorodeoxyglucose positron emission tomography scanning in diagnosing aortic prosthetic graft infection
Published in: European Journal of Nuclear Medicine and Molecular Imaging
BACKGROUND: The clinical problem in suspected aortoiliac graft infection (AGI) is to obtain proof of infection. Although (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography scanning (PET) has been suggested to play a pivotal role, an evidence-based interpretation is lacking. The objective of this retrospective study was to examine the feasibility and utility of (18)F-FDG uptake heterogeneity characterized by textural features to diagnose AGI. METHODS: Thirty patients with a history of aortic graft reconstruction who underwent (18)F-FDG PET/CT scanning were included. Sixteen patients were suspected to have an AGI (group I)....
Predictive Value of Renal Transplant Scintigraphy for the Duration of Delayed Graft Function
Clinical and 123I-SAP scintigraphy findings in three members from a family affected by AGel amyloidosis
Published in: Amyloid
Pancreatic Uptake by F-18-FDOPA PET/CT in Patients With Hypoglycemia After Gastric Bypass Surgery Compared With Controls With or Without Carbidopa Pretreatment
Published in: Clinical Nuclear Medicine
Purpose: The use of 18Fluorine-labeled dihydroxy-phenyl-alanine (F-18-FDOPA) PET/CT in patients with hypoglycemia suspected to be caused by pancreatic disease can be helpful to localize the source of excess insulin production. In this setting, carbidopa pretreatment is not recommended. However, quantitative comparisons of pancreatic tracer uptake in patients with or without carbidopa pretreatment and in diffuse pancreatic disease are lacking. Therefore, we aimed to describe and quantify pancreatic F-18-FDOPA uptake in patients without pancreatic disease with or without carbidopa pretreatment and in patients with hypoglycemia after gastric bypass surgery....
Effect of Linagliptin on Arterial (18)F-Fluorodeoxyglucose Positron Emission Tomography Uptake: A Randomized Controlled Trial (RELEASE)
Published in: Journal of the American College of Cardiology
