Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology
Published in: European Heart Journal - Cardiovascular Imaging
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10.1093/ehjci/jex146
document
This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with F-18-fluorodeoxyglucose positron emission tomography, radionuclide myocardial perfusion imaging and cardiovascular magnetic resonance imaging for the evaluation and management of patients with known or suspected cardiac sarcoidosis. This position paper will aid in standardizing imaging for cardiac sarcoidosis and may facilitate clinical trials and pooling of multi-centre data on cardiac sarcoidosis. Proposed flow charts for the work up and management of cardiac sarcoidosis are included.
Riemer H J A Slart, Andor W J M Glaudemans, Patrizio Lancellotti, Fabien Hyafil, Ron Blankstein, Ronald G Schwartz, Wael A Jaber, Raymond Russell, Alessia Gimelli, François Rouzet, Marcus Hacker, Olivier Gheysens, Sven Plein, Edward J Miller, Sharmila Dorbala, Erwan Donal, Document Reading Group
Detection of Osteomyelitis in the Diabetic Foot by Imaging Techniques: A Systematic Review and Meta-analysis Comparing MRI, White Blood Cell Scintigraphy, and FDG-PET
Published in: Diabetes Care
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10.2337/dc17-0532
OBJECTIVE: Diagnosing bone infection in the diabetic foot is challenging and often requires several diagnostic procedures, including advanced imaging. We compared the diagnostic performances of MRI, radiolabeled white blood cell (WBC) scintigraphy (either with (99m)Tc-hexamethylpropyleneamineoxime [HMPAO] or (111)In-oxine), and [(18)F]fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET)/computed tomography. RESEARCH DESIGN AND METHODS: We searched Medline and Embase as of August 2016 for studies of diagnostic tests on patients known or suspected to have diabetes and a foot infection. We performed a systematic review using criteria recommended by the Cochrane Review of...
Chiara Lauri, Menno Tamminga, Andor W J M Glaudemans, Luis Eduardo Juárez Orozco, Paola A Erba, Paul C Jutte, Benjamin A. Lipsky, Maarten J IJzerman, Alberto Signore, Riemer H J A Slart
F-18-FES PET Has Added Value in Staging and Therapy Decision Making in Patients With Disseminated Lobular Breast Cancer
Published in: Clinical Nuclear Medicine
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10.1097/RLU.0000000000001724
Lobular breast cancer is the second most common type of invasive breast cancer. Lobular breast cancer lesions are often difficult to detect with conventional imaging because they tend to grow less cohesively than ductal cancer. These images represent 3 lobular breast cancer cases, in whom confirmation of metastatic disease would make the crucial difference between curative or noncurative treatment. Staging with conventional imaging, however, yielded equivocal results, and a biopsy was not feasible. In contrast, FES (16 alpha-[F-18]fluoro-17 beta-estradiol) PET provided a decisive contribution to clinical decision making...
FDG-PET/CT as a New Method for Diagnosis and Whole-Body Evaluation of Lemierre Syndrome
Published in: Clinical Nuclear Medicine
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10.1097/RLU.0000000000001708
Lemierre syndrome is a rare disease that is defined by a pharyngeal infection, complicated by septicemia and internal jugular vein thrombosis followed by septic emboli. Because of its rarity, a delay in diagnosis is not uncommon. However, given the mortality rate of approximately 2%, prompt diagnosis and detection of septic emboli are essential to initiate prompt treatment, preventing organ damage and ongoing sepsis. We present 3 cases that demonstrate the value of FDG-PET/CT as a possible alternative or adjunct to conventional imaging methods for diagnosis and whole-body evaluation...
Late onset cardiomyopathy as presenting sign of ATTR A45G amyloidosis caused by a novel TTR mutation (p.A65G)
Published in: Cardiovascular Pathology
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10.1016/j.carpath.2017.04.002
document
Objective: The clinical description of a novel TTR genemutation characterized by a late onset amyloid cardiomyopathy. Methods and Results: A 78-year-old man of Dutch origin with recent surgeryforbilateral carpal tunnel syndrome(CTS) was admitted to our hospital because of heart failure with preserved ejection fraction (55%). Cardiac ultrasound showed thickened biventricular walls, and cardiac magnetic resonance imaging also showed late gadolinium enhancement. Early signs of a polyneuropathy were found by neurophysiological testing. A few months later, his 72year- old sister was admitted to an affiliated hospital because of heart...
Sebastiaan H. C. Klaassen, Henny H. Lemmink, Johan Bijzet, Andor W. J. M. Glaudemans, Reinhard Bos, Wouter Plattel, Maarten P. van den Berg, Riemer H. J. A. Slart, Hans L. A. Nienhuis, Dirk J. van Veldhuisen, Bouke P. C. Hazenberg