Walter Noordzij
dr.
In my profession as a nuclear medicine physician, I’m involved in both clinical and scientific applications of nuclear medicine and radiology modalities. My main interests include haematology, general oncology, radio-immunotherapy, and especially the implementation of new therapeutic strategies. Currently, I have a special interest in imaging post-transplant lymphoproliferative disease, as well as radio-immunotherapy in chemotherapy refractory (non)-Hodgkin’s lymphoma.
Increased individual workload for nuclear medicine physicians over the past years: 2008-2023 data from The Netherlands
Published in: Annals of Nuclear Medicine
Access to document
10.1007/s12149-024-01995-5
document
OBJECIVE: To investigate temporal trends in the individual workload of nuclear medicine physicians at a large tertiary care academic center between 2008 and 2023. METHODS: This study analyzed the reporting workload of nuclear medicine physicians in a large tertiary care academic center in The Netherlands on 36 unique (randomly sampled) calendar days, for each year between 2008 and 2023. The average daily departmental workload (measured with relative value units) was calculated for each year between 2008 and 2023. The individual workload was calculated by dividing the average daily...
Asaad A H Amasha, Ömer Kasalak, Andor W J M Glaudemans, Walter Noordzij, Rudi A J O Dierckx, Klaas-Pieter Koopmans, Thomas C Kwee
Feasibility of the Absolute Quantification and Left Ventricular Segmentation of Cardiac Sympathetic Innervation in Wild-type Transthyretin Amyloidosis Cardiomyopathy with [123I]-MIBG SPECT/CT: the I-NERVE study.
Published in: Journal of Nuclear Cardiology
Access to document
10.1016/j.nuclcard.2025.102146
document
PURPOSE: Cardiac sympathetic neuronal dysfunction is an early marker in wild-type transthyretin amyloidosis cardiomyopathy (ATTRwt-CM). [ 123I]-MIBG imaging evaluates cardiac sympathetic innervation but lacks volumetric activity quantification in current methods. This study aims to quantify cardiac sympathetic neuronal dysfunction in ATTRwt-CM using [ 123I]-MIBG SPECT/CT and correlate findings with functional and structural cardiac parameters from echocardiogram and cardiac magnetic resonance imaging (CMR). METHODS: We conducted a single-center, descriptive, cross-sectional study to quantify absolute myocardial sympathetic function in ATTRwt-CM using [ 123I]-MIBG SPECT/CT. Retrospective reconstruction allowed for absolute tracer-uptake...
Alwin Tubben, Niek H J Prakken, Oleksandra V Ivashchenko, Hendrea S A Tingen, Andor W J M Glaudemans, Walter Noordzij, Hans L A Nienhuis, Peter van der Meer, Riemer H J A Slart
Paediatric Dose Optimization for Long Axial Field-ofView FDG PET/CT
Aim/Introduction: Paediatric patients are more radiationsensitive, therefore minimizing exposure during imaging is vital, while tailoring protocols to their varying sizes and ages is complex. The European Association of Nuclear Medicine (EANM) developed the paediatric dose card, a tool helping to determine safe and sufcient tracer activity levels. This dose card relies on data from large retrospective paediatric patient cohorts. Consequently failing to incorporate recent breakthroughs in whole-body and long axial feld-of-view (LAFOV) PET/CT imaging, which hold signifcant promise for reducing radiation exposure in children. This study evaluates the...
Scan speed reduction in post-therapy [177Lu]LuPSMA SPECT/CT: How fast can we go without afecting accuracy of dosimetry calculations?
Aim/Introduction: Accurate dose estimation in [177Lu]LuPSMA therapy is crucial for organs at risk such as the kidneys. However, the current method involves lengthy scans, causingdiscomfort for patients with bone metastases common in prostate cancer, fnancial pressure and image quality problems due to the motion. Our research aims to optimise this process byinvestigating acceptable scan reduction while maintaining the accuracy of the calculate dose to organs at risk. Materials and Methods: A total of 11 post-therapy imaging sequences from patients undergoing [177Lu]Lu-PSMA therapy were selected. For each, two post-therapy...
Paediatric Dose Optimization for Long Axial Field-ofView FDG PET/CT
Aim/Introduction: Paediatric patients are more radiationsensitive, therefore minimizing exposure during imaging is vital, while tailoring protocols to their varying sizes and ages is complex. The European Association of Nuclear Medicine (EANM) developed the paediatric dose card, a tool helping to determine safe and sufcient tracer activity levels. This dose card relies on data from large retrospective paediatric patient cohorts. Consequently failing to incorporate recent breakthroughs in whole-body and long axial feld-of-view (LAFOV) PET/CT imaging, which hold signifcant promise for reducing radiation exposure in children. This study evaluates the...