Walter Noordzij
dr.
In my profession as a nuclear medicine physician, I’m involved in both clinical and scientific applications of nuclear medicine and radiology modalities. My main interests include haematology, general oncology, radio-immunotherapy, and especially the implementation of new therapeutic strategies. Currently, I have a special interest in imaging post-transplant lymphoproliferative disease, as well as radio-immunotherapy in chemotherapy refractory (non)-Hodgkin’s lymphoma.
Effects of proton therapy on regional [18F]FDG uptake in non-tumor brain regions of patients treated for head and neck cancer
Published in: Clinical and Translational Radiation Oncology
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10.1016/j.ctro.2023.100652
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Background and purpose: Previous pre-clinical research using [18F]FDG-PET has shown that whole-brain photon-based radiotherapy can affect brain glucose metabolism. This study, aimed to investigate how these findings translate into regional changes in brain [18F]FDG uptake in patients with head and neck cancer treated with intensity-modulated proton therapy (IMPT). Materials and methods: Twenty-three head and neck cancer patients treated with IMPT and available [18F]FDG scans before and at 3 months follow-up were retrospectively evaluated. Regional assessment of the [18F]FDG standardized uptake value (SUV) parameters and radiation dose in the...
Wejdan M. Arif, Philip H. Elsinga, Roel J. H. M. Steenbakkers, Walter Noordzij, Lara Barazzuol, Kelvin N.G.Wei Siang, Charlotte L. Brouwer, Bruno Lima Giacobbo, Rudi A. J. O. Dierckx, Ronald J. H. Borra, Gert Luurtsema
A dual-tracer approach using [11C]CH and [18F]FDG in HCC clinical decision making
Published in: EJNMMI Research
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10.1186/s13550-023-01024-y
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BACKGROUND: Early detection of recurrent or progressive HCC remains the strongest prognostic factor for survival. Dual tracer PET/CT imaging with [11C]CH and [18F]FDG can further increase detection rates as both tracers entail different metabolic pathways involved in HCC development. We investigated dual-tracer PET/CT in clinical decision making in patients suspected of recurrent or progressive HCC. All HCC patients who underwent both [11C]CH and [18F]FDG PET/CT in our institute from February 2018 to December 2021 were included. Both tracer PET/CT were within 4 weeks of each other with at...
Emile B Veenstra, Simeon J S Ruiter, Robbert J de Haas, Koert P de Jong, Paola A Erba, Rudi A J O Dierckx, Walter Noordzij
[15O]H2O PET: Potential or Essential for Molecular Imaging?
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2023.08.002
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Imaging water pathways in the human body provides an excellent way of measuring accurately the blood flow directed to different organs. This makes it a powerful diagnostic tool for a wide range of diseases that are related to perfusion and oxygenation. Although water PET has a long history, its true potential has not made it into regular clinical practice. The article highlights the potential of water PET in molecular imaging and suggests its prospective role in becoming an essential tool for the 21st century precision medicine in different...
Riemer H J A Slart, T Samara Martinez-Lucio, Hendrikus H Boersma, Ronald H Borra, Bart Cornelissen, Rudi A J O Dierckx, Magdalena Dobrolinska, Janine Doorduin, Paola A Erba, Andor W J M Glaudemans, Bruno Lima Giacobbo, Gert Luurtsema, Walter Noordzij, Joyce van Sluis, Charalampos Tsoumpas, Adriaan A Lammertsma
The radiology job market in the Netherlands: which subspecialties and other skills are in demand?
Published in: European Radiology
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10.1007/s00330-023-09983-5
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Objectives: To evaluate the current job market for medical specialists in radiology and nuclear medicine (NM) in the Netherlands. Methods: Vacancies posted for radiologists and nuclear medicine physicians in the Netherlands between December 2020 and February 2022 were collected and analyzed. Results: A total of 157 vacancies (146 for radiologist and 11 for nuclear medicine physicians) were included. The most sought-after subspecialties were all-round (22%), abdominal (19%), and interventional radiology (14%), and 30% of vacancies preferred applicants with additional non-clinical skills (research, teaching, management, information and communications technology...
External validation of 18 F-FDG PET-based radiomic models on identification of residual oesophageal cancer after neoadjuvant chemoradiotherapy
Published in: Nuclear Medicine Communications
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10.1097/MNM.0000000000001707
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OBJECTIVES: Detection of residual oesophageal cancer after neoadjuvant chemoradiotherapy (nCRT) is important to guide treatment decisions regarding standard oesophagectomy or active surveillance. The aim was to validate previously developed 18 F-FDG PET-based radiomic models to detect residual local tumour and to repeat model development (i.e. ‘model extension’) in case of poor generalisability. METHODS: This was a retrospective cohort study in patients collected from a prospective multicentre study in four Dutch institutes. Patients underwent nCRT followed by oesophagectomy between 2013 and 2019. Outcome was tumour regression grade (TRG) 1...
Maria J Valkema, Roelof J Beukinga, Avishek Chatterjee, Henry C Woodruff, David van Klaveren, Walter Noordzij, Roelf Valkema, Roel J Bennink, Mark J Roef, Wendy Schreurs, Michail Doukas, Sjoerd M Lagarde, Bas P L Wijnhoven, Philippe Lambin, John T M Plukker, J Jan B van Lanschot