I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists.
Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Recommendations in Clinical F-Fluoro-2-Deoxy-D-Glucose PET/CT Reports: Referring Physicians’ Compliance and Diagnostic Yield
Published in: Journal of the american college of radiology
PURPOSE: To investigate how frequently and when referring physicians follow the recommendation in an 18F-fluoro-2-deoxy-D-glucose PET/CT (FDG-PET/CT) report and to determine the diagnostic yield of these recommendations. MATERIALS AND METHODS: This retrospective study included 2,496 clinical FDG-PET/CT scans that were performed at a tertiary care academic medical center in a 1.5-year period. The following variables were extracted from each report that contained a recommendation: patient age, patient gender, hospital status (inpatient versus outpatient), indication for FDG-PET/CT scanning, descriptive clarity of the recommendation, type of recommendation (additional imaging versus...
Infection and inflammation imaging standardization: the EANM guidelines
Published in: Clinical and Translational Imaging
F-18-Fluoroestradiol Tumor Uptake Is Heterogeneous and Influenced by Site of Metastasis in Breast Cancer Patients
Published in: Journal of Nuclear Medicine
Heterogeneity of estrogen receptor (ER) expression in breast cancer is recognized. However, knowledge about varying expression across metastases and surrounding normal tissue in patients is scarce. We therefore analyzed 16 alpha-F-18-fluoro-17 beta-estradiol (F-18-FES) PET to assess ER expression heterogeneity. Methods: F-18-FES PET on accredited PET/CT camera systems performed in patients with ER-positive metastatic breast cancer November 2009-December 2014 was analyzed. Lesions with an SUVmax 1.5 or more were considered ER-positive, but liver lesions were excluded given high background liver signal. CT lesions with a diameter 10 mm or...
Have we forgotten imaging prior to and after kidney transplantation?
Published in: European Radiology
• The number of publications on imaging and kidney transplantation is low. • These publications are poorly cited, as compared with other fields of imaging. • Conversely, there is a clinical need for evidence-based recommendations. • Innovative advances for the use of imaging and kidney transplantation are essential. • An increased focus and adequate research funding are highly anticipated by clinicians.
Blind Spots in Evidence-Based Medicine: The Lack of Knowledge on Imaging and Kidney Transplantation
