Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Can transplant renal scintigraphy predict the duration of delayed graft function? A dual center retrospective study: A dual center retrospective study
Published in: PLoS ONE
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10.1371/journal.pone.0193791
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Introduction This study focused on the value of quantitatively analyzed and qualitatively graded renal scintigraphy in relation to the expected duration of delayed graft function after kidney transplantation. A more reliable prediction of delayed graft function duration may result in a more tailored and patient-specific treatment regimen post-transplantation. Methods From 2000 to 2014, patients with early transplant dysfunction and a Tc-99m MAG3 renal scintigraphy, within 3 days post-transplantation, were included in a dual center retrospective study. Time-activity curves of renal scintigraphy procedures were qualitatively graded and various quantitative...
Stan Benjamens, Robert A Pol, Lioe-Fee de Geus-Oei, Aiko P J de Vries, Andor W J M Glaudemans, Stefan P Berger, Riemer H J A Slart
Hybrid imaging of musculoskeletal infections
Published in: Quarterly Journal of Nuclear Medicine and Molecular Imaging
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10.23736/S1824-4785.17.03045-X
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This review article highlights the role of radiological and nuclear medicine techniques in diagnosis of musculoskeletal infections with particular regard to hybrid imaging of osteomyelitis, prosthetic joint infections, sternal infections and spine infections. Authors conclude on the complementary role of the several techniques with indications for an appropriate diagnostic flow chart, in the light of the recent EANM guidelines on infection.
Andor W Glaudemans, Napoleone Prandini, Marco DI Girolamo, Giuseppe Argento, Chiara Lauri, Elena Lazzeri, Mario Muto, Luca M Sconfienza, Alberto Signore
Tuberculosis
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2017.10.005
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Tuberculosis (TB) is currently the world’s leading cause of infectious mortality. Imaging plays an important role in the management of this disease. The complex immune response of the human body to Mycobacterium tuberculosis results in a wide array of clinical manifestations, making clinical and radiological diagnosis challenging. F-18-FDG-PET/CT is very sensitive in the early detection of TB in most parts of the body; however, the lack of specificity is a major limitation. F-18-FDG-PET/CT images the whole body and provides a pre-therapeutic metabolic map of the infection, enabling clinicians...
Alfred O Ankrah, Andor W J M Glaudemans, Alex Maes, Christophe Van de Wiele, Rudi A J O Dierckx, Mariza Vorster, Mike M Sathekge
Radiological and nuclear medicine imaging of sarcoidosis
Published in: Quarterly Journal of Nuclear Medicine and Molecular Imaging
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10.23736/S1824-4785.17.03046-1
Sarcoidosis is a multisystem chronic inflammatory disease of unknown etiology characterized by widespread growth of non-caseating granulomas. The diagnosis of sarcoidosis is based on clinical and imaging presentation, histologic confirmation and the absence of alternative diseases. Radiology and Nuclear Medicine play an essential role in the diagnostic work-up of patients with sarcoidosis to assess disease extent and activity. In addition, imaging modalities have shown their potential in managing these patients in terms of treatment response and prognostic assessment. Sarcoidosis has a predilection for chest involvement, showing typical and...
Anna R Larici, Andor W Glaudemans, Annemilia Del Ciello, Riemer H Slart, Lucio Calandriello, Olivier Gheysens
Can FDG-PET/CT replace blind bone marrow biopsy of the posterior iliac crest in Ewing sarcoma?
Published in: Skeletal Radiology
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10.1007/s00256-017-2807-2
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OBJECTIVE: To determine and compare the value of (18)F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) to blind bone marrow biopsy (BMB) of the posterior iliac crest in detecting metastatic bone marrow involvement in newly diagnosed Ewing sarcoma. MATERIALS AND METHODS: This retrospective study included 20 patients with newly diagnosed Ewing sarcoma who underwent pretreatment FDG-PET/CT and a total of 38 blind BMBs (two unilateral and 18 bilateral) of the posterior iliac crest. FDG-PET/CT scans were evaluated for bone marrow involvement, both in the posterior iliac crest and other sites,...