Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Treatment and Follow-up of Vascular Graft and Endograft Infection: Delphi Consensus Document
Published in: Clinical Microbiology and Infection
Access to document
10.1016/j.cmi.2025.07.020
document
SCOPE: Vascular graft or endograft infection (VGEI) is a severe complication requiring a multidisciplinary approach combining surgery and antimicrobial therapy. This study aimed to develop expert consensus on the management and follow-up of VGEI, with a focus on antimicrobial strategies. METHODS: A modified Delphi method was conducted to reach consensus on key aspects of VGEI care, including antimicrobial treatment, surgical management, and follow-up. An expert panel representing infectious diseases, vascular and cardiothoracic surgery, microbiology, and nuclear medicine participated in four rounds of surveys. Ten general and 35 specific...
Ilse J E Kouijzer, Marta Hernández-Meneses, Erik H J G Aarntzen, Jonas Ahl, Larry M Baddour, Daniel C DeSimone, Emanuele Durante Mangoni, Nuria Fernández-Hidalgo, Guillaume S C Geuzebroek, Efthymia Giannitsioti, Andor W J M Glaudemans, Lars Husmann, Marco Merli, Carlos A Mestres, Flaminia Olearo, Matthaios Papadimitriou-Olivgeris, Nis Pedersen Jørgensen, Andrés Perissinotti, Annibale Raglio, Zoran RancicAkshatha Ravindra, Benedikt Reutersberg, Leonardo Francesco Rezzonico, Marco Ripa, Petar Risteski, Alessandro Russo, Ben Saleem, Karl Sörelius, Dolores Sousa, Pierre Tattevin, Marjan Wouthuyzen-Bakker, Thomas R Wyss, Xavier Yugueros, Alexander Zimmermann, Barbara Hasse
Positron Emission Tomography Imaging in Vasculitis
Published in: Heart failure clinics
Access to document
10.1016/j.hfc.2025.01.007
Systemic vasculitides comprise a group of autoimmune diseases affecting blood vessels. [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) plays an important role in the diagnosis and therapeutic monitoring of vasculitides affecting large-sized and medium-sized vessels. FDG-PET/CT also provides complementary information to other vascular imaging tools. The resolution and sensitivity of newer generation scanners continues to increase, hereby improving the ability of FDG-PET/CT to accurately assess the full disease extent in patients with vasculitis. Novel tracers targeting specific immune cells will allow for more detailed detection of vascular infiltrates.
Kornelis S M van der Geest, Berend G C Slijkhuis, Alessandro Tomelleri, Olivier Gheysens, William F Jiemy, Costanza Piccolo, Pieter Nienhuis, Maria Sandovici, Elisabeth Brouwer, Andor W J M Glaudemans, Douwe J Mulder, Riemer H J A Slart
Current Developments on [18F]FDG PET/CT in Inflammatory Disorders of the Central Nervous System.
Published in: Seminars in Nuclear Medicine
Access to document
10.1053/j.semnuclmed.2025.06.001
document
2-Deoxy-2-[ 18F]fluoro-D-glucose positron emission tomography (FDG-PET) is widely used to study cerebral glucose metabolism and may be useful in several inflammatory disorders of the central nervous system. Emerging literature suggests that [ 18F]FDG may be more sensitive to detect abnormalities in auto-immune encephalitis (AIE) in comparison to MRI, especially in NDMA receptor encephalitis. Distinct patterns of regional abnormalities in AIE have been reported, depending on the auto-antibody involved. Predominant findings are hypermetabolism of the mediotemporal lobe and hypometabolism in parietal and occipital lobes. The possibility for whole body...
The diagnostic role of 2-[18F]FDG PET/CT in critically ill patients with suspected infection of unknown origin: a real-world experience
Published in: Radiologia medica
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10.1007/s11547-025-02005-y
document
PURPOSE: 2-Deoxy-2-[ 18F]-fluoro-D-glucose (2-[ 18F]FDG) positron emission tomography/computed tomography (PET/CT) is a hybrid imaging tool with an emerging role in the study of several infectious and inflammatory diseases. Its role in critically ill patients admitted to the intensive care unit (ICU) is only marginally investigated. This study aimed to investigate the diagnostic performance and the clinical impact of 2-[ 18F]FDG PET/CT in the management of critically ill patients with suspected infections of unknown origin. METHODS: We retrospectively included 47 ICU patients (mean age 63.6 years, 33 males) who...
Domenico Albano, Carlo Rodella, Anna Calabrò, Andor W J M Glaudemans, Giorgio Treglia, Francesco Bertagna
[68Ga]FAPI PET/CT reveals increased pulmonary fibroblast activation protein expression in long COVID patients after ICU discharge.
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document
10.1007/s00259-025-07376-y
document
PURPOSE: Post-acute sequelae of COVID-19 (PASC) has emerged as a major healthcare problem. A comprehensive mechanism of disease remains to be elucidated. In this study we aimed to explore pulmonary and muscle fibroblast activation protein (FAP) activity in former critical COVID-19 patients with persistent dyspnea, using [ 68Ga]FAPI-46 PET/CT. METHODS: In this single center prospective observational study we included former critical COVID-19 patients reporting complaints of dyspnea > 3 months after hospital discharge. A [ 68Ga]FAPI PET/CT scan was performed including a high-resolution CT scan, lung function test, EQ-5D questionnaire,...
COVID-CLIMATE consortium, B van Leer, M Londema, Ö Kasalak, J H van Snick, M L Duiverman, J C Kuijvenhoven, M D de Kruif, D E Oprea-Lager, K Pabst, M E Hellemons, H H Boersma, M Prokop, M W Nijsten, A W J M Glaudemans, J Pillay, R H J A Slart