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Andor Glaudemans
prof. dr.

I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.

Diagnostic performance and image interpretation of 18F-FDG PET/CT in aortic graft infection: Two sides of the same coin
Published in: Journal of Nuclear Cardiology
Access to document 10.1007/s12350-020-02029-z document
Giorgio Treglia, Riemer H J A Slart, Andor W J M Glaudemans
Added value of 18F-FDG-PET/CT and cardiac CTA in suspected transcatheter aortic valve endocarditis
Published in: Journal of Nuclear Cardiology
Access to document 10.1007/s12350-019-01963-x document
BACKGROUNDS: Transcatheter-implanted aortic valve infective endocarditis (TAVI-IE) is difficult to diagnose when relying on the Duke Criteria. Our aim was to assess the additional diagnostic value of 18F-fluorodeoxyglucose (18F-FDG) positron emission/computed tomography (PET/CT) and cardiac computed tomography angiography (CTA) in suspected TAVI-IE. METHODS: A multicenter retrospective analysis was performed in all patients who underwent 18F-FDG-PET/CT and/or CTA with suspected TAVI-IE. Patients were first classified with Duke Criteria and after adding 18F-FDG-PET/CT and CTA, they were classified with European Society of Cardiology (ESC) criteria. The final diagnosis was determined...
Ali R Wahadat, Wilco Tanis, Laurens E Swart, Asbjørn Scholtens, Gabriel P Krestin, Nicolas M D A van Mieghem, Carolina A M Schurink, Tycho I G van der Spoel, Floris S van den Brink, Tessel Vossenberg, Riemer H J A Slart, Andor W J M Glaudemans, Jolien W Roos-Hesselink, Ricardo P J Budde
The effects of molar activity on [F-18]FDOPA uptake in patients with neuroendocrine tumors
Published in: EJNMMI Research
Access to document 10.1186/s13550-021-00829-z document
BACKGROUND: 6-[18F]fluoro-L-3,4-dihydroxyphenyl alanine ([18F]FDOPA) is a commonly used PET tracer for the detection and staging of neuroendocrine tumors. In neuroendocrine tumors, [18F]FDOPA is decarboxylated to [18F]dopamine via the enzyme amino acid decarboxylase (AADC), leading to increased uptake when there is increased AADC activity. Recently, in our hospital, a new GMP compliant multi-dose production of [18F]FDOPA has been developed, [18F]FDOPA-H, resulting in a higher activity yield, improved molar activity and a lower administered mass than the conventional method ([18F]FDOPA-L). AIMS: This study aimed to investigate whether the difference in...
Gilles N Stormezand, Romano S B H Schreuder, Adrienne H Brouwers, Riemer H J A Slart, Philip H Elsinga, Annemiek M E Walenkamp, R A J O Dierckx, Andor W J M Glaudemans, Gert Luurtsema
EANM recommendations based on systematic analysis of small animal radionuclide imaging in inflammatory musculoskeletal diseases
Published in: EJNMMI Research
Access to document 10.1186/s13550-021-00820-8 document
Inflammatory musculoskeletal diseases represent a group of chronic and disabling conditions that evolve from a complex interplay between genetic and environmental factors that cause perturbations in innate and adaptive immune responses. Understanding the pathogenesis of inflammatory musculoskeletal diseases is, to a large extent, derived from preclinical and basic research experiments. In vivo molecular imaging enables us to study molecular targets and to measure biochemical processes non-invasively and longitudinally, providing information on disease processes and potential therapeutic strategies, e.g. efficacy of novel therapeutic interventions, which is of complementary value...
Erik H J G Aarntzen, Edel Noriega-Álvarez, Vera Artiko, André H Dias, Olivier Gheysens, Andor W J M Glaudemans, Chiara Lauri, Giorgio Treglia, Tim van den Wyngaert, Fijs W B van Leeuwen, Samantha Y A Terry
Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study
Published in: JACC: Asia
Access to document 10.1016/j.jacasi.2021.06.002 document
Background: The coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known. Objectives: This study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia. Methods: The International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and...
INCAPS COVID Investigators Group, Takashi Kudo, Ryan Lahey, Cole B. Hirschfeld, Michelle C. Williams, Bin Lu, Mirvat Alasnag, Mona Bhatia, Hee Seung Henry Bom, Tairkhan Dautov, Reza Fazel, Ganesan Karthikeyan, Felix Y.J. Keng, Ronen Rubinshtein, Nathan Better, Rodrigo Cerci, Sharmila Dorbala, Paolo Raggi, Leslee J. Shaw, Todd C. VillinesJoão V. Vitola, Andrew Choi, Eli Malkovskiy, Benjamin Goebel, Yosef Cohen, Michael Randazzo, Thomas N.B. Pascual, Yaroslav Pynda, Maurizio Dondi, Diana Paez, Andrew J. Einstein