Walter Noordzij
dr.
In my profession as a nuclear medicine physician, I’m involved in both clinical and scientific applications of nuclear medicine and radiology modalities. My main interests include haematology, general oncology, radio-immunotherapy, and especially the implementation of new therapeutic strategies. Currently, I have a special interest in imaging post-transplant lymphoproliferative disease, as well as radio-immunotherapy in chemotherapy refractory (non)-Hodgkin’s lymphoma.
The pattern of local recurrence after prostatectomy on PSMA PET/CT-scan
Published in: Tijdschrift voor Urologie
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10.1007/s13629-024-00424-6
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This study aimed to describe the local recurrence (LR) pattern in post-prostatectomy prostate cancer patients using PSMA PET/CT scans. We retrospectively collected 103 PSMA PET/CT scans from patients with suspected LR across nine medical centres. Anonymized scans underwent review by an expert nuclear medicine physician. After review, on 83 PSMA PET/CT scans, 93 lesions were identified as a LR. The predominant LR location (56%) was found within 2 cm cranial to the penile bulb. Additionally, 24 LR (26%) were observed > 2 cm cranial to the penile bulb and caudal to the top of the...
Floor H.E. Staal, Walter Noordzij, Jorinde Janssen, Daniëla E. Oprea-Lager, Antoine M. Engelen, Evert J. van Limbergen, Robert Jan Smeenk, Marianne A.A. de Jong, Tom C.G. Budiharto, Inge Jacobs, M. A.Dorien Haverkort, Charlotte L. Brouwer, Kelvin Ng Wei Siang, Johannes A. Langendijk, J. Fred Verzijlbergen, Igle Jan de Jong, Shafak Aluwini
Reading room assistants to reduce workload and interruptions of radiology residents during on-call hours: Initial evaluation
Published in: European Journal of Radiology
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10.1016/j.ejrad.2024.111381
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PURPOSE: To determine how much timesaving and reduction of interruptions reading room assistants can provide by taking over non-image interpretation tasks (NITs) from radiology residents during on-call hours. METHODS: Reading room assistants are medical students who were trained to take over NITs from radiology residents (e.g. answering telephone calls, administrative tasks and logistics) to reduce residents’ workload during on-call hours. Reading room assistants’ and residents’ activities were tracked during 6 weekend dayshifts in a tertiary care academic center (with more than 2.5 million inhabitants in its catchment area)...
Reducing and controlling metabolic active tumor volume prior to CAR T-cell infusion can improve survival outcomes in patients with large B-cell lymphoma
Published in: Blood cancer journal
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10.1038/s41408-024-01022-w
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Bridging therapy before CD19-directed chimeric antigen receptor (CAR) T-cell infusion is frequently applied in patients with relapsed or refractory Large B-cell lymphoma (r/r LBCL). This study aimed to assess the influence of quantified MATV and MATV-dynamics, between pre-apheresis (baseline) and pre-lymphodepleting chemotherapy (pre-LD) MATV, on CAR T-cell outcomes and toxicities in patients with r/r LBCL. MATVs were calculated semi-automatically at baseline (n = 74) and pre-LD (n = 68) in patients with r/r LBCL who received axicabtagene ciloleucel. At baseline, patients with a low MATV (< 190 cc) had a better time to...
PSMA PET/CT based clinical target volume delineation guideline for post-prostatectomy salvage radiation therapy: the PERYTON-Guideline
Published in: International Journal of Radiation Oncology, Biology, Physics
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10.1016/j.ijrobp.2023.09.016
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PURPOSE: PSMA PET/CT scan is the standard imaging procedure for biochemical recurrent prostate cancer post-prostatectomy due to its high detection rate at low serum PSA levels. However, existing guidelines for clinical target volume (CTV) in prostate bed salvage external beam radiation therapy (sEBRT) are primarily based on experience-based clinical consensus and have been validated using conventional imaging modalities. Therefore, this study aimed to optimize CTV definition in sEBRT by utilizing PSMA PET/CT-detected local recurrences (LRs). METHODS AND MATERIALS: Patients with suspected LR on PSMA PET/CT post-prostatectomy were retrospectively...
F H E Staal, J Janssen, D E Oprea-Lager, A M Engelen, E J van Limbergen, R J Smeenk, M A A de Jong, T C G Budiharto, I Jacobs, M A D Haverkort, C L Brouwer, K Ng Wei Siang, J A Langendijk, J F Verzijlbergen, I J de Jong, W Noordzij, S Aluwini
Is work overload associated with diagnostic errors on 18F-FDG-PET/CT?
Published in: European Journal of Nuclear Medicine and Molecular Imaging
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10.1007/s00259-023-06543-3
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PURPOSE: To determine the association between workload and diagnostic errors on 18F-FDG-PET/CT. MATERIALS AND METHODS: This study included 103 18F-FDG-PET/CT scans with a diagnostic error that was corrected with an addendum between March 2018 and July 2023. All scans were performed at a tertiary care center. The workload of each nuclear medicine physician or radiologist who authorized the 18F-FDG-PET/CT report was determined on the day the diagnostic error was made and normalized for his or her own average daily production (workload normalized). A workload normalized of more than...