Skip to main content
Arjan Diepstra
dr.

As a hematopathologist, I work on diagnostics of all types of hematological malignancies using a comprehensive panel of different techniques. Moreover, my main research interest involves Hodgkin lymphoma, with a strong focus on interactions between tumor cells and the microenvironment. In addition, I also have a long standing interest in genetic susceptibility. My areas of expertise are: immunology, tumor cell biology, genetic association studies and molecular diagnostics in pathology. I actively participate in international (EORTC) and national (HOVON) clinical trials.

PROSPECTIVE ANALYSIS OF PLASMA LEVELS OF THYMUS AND ACTIVATION REGULATED CHEMOKINE (TARC) IN PRIMARY AND RELAPSED CLASSICAL HODGKIN LYMPHOMA PATIENTS
W. Plattel, A. van den Berg, A. M. Van der Graaf, S. Poppema, L. Visser, A. Diepstra, G. W. Van Imhoff
EXPRESSION AND FUNCTION OF TOLL LIKE RECEPTORS TLR4, TLR7 AND TLR9 IN CLASSICAL HODGKIN LYMPHOMA
C. Xu, L. Visser, A. Diepstra, P. Moeller, S. Poppema, A. van den Berg
HLA EXPRESSION AND GENETIC ASSOCIATIONS IN EBV POSITIVE AND EBV NEGATIVE CLASSICAL HODGKIN LYMPHOMA
A. Diepstra, B. Hepkema, H. Xin, C. Xu, K. Kushekhar, R.J.M. Nolte, L. Visser, S. Poppema, A. van den Berg
Expression of CD1d and presence of invariant NKT cells in classical Hodgkin lymphoma
Published in: American Journal of Hematology
Access to document 10.1002/ajh.21743
Chuanhui Xu, Riemer de Vries, Lydia Visser, Arjan Diepstra, Stephan D. Gadola, Sibrand Poppema, Anke van den Berg
Expression of HLA Class I and HLA Class II by Tumor Cells in Chinese Classical Hodgkin Lymphoma Patients
Published in: PLoS ONE
Access to document 10.1371/journal.pone.0010865 document
Background: In Caucasian populations, the tumor cells of Epstein Barr virus (EBV)-positive classical Hodgkin Lymphomas (cHL) patients more frequently express HLA class I and HLA class II molecules compared to EBV-negative cHL patients. HLA expression (in relation to EBV) in Asian cHL patients has not been previously investigated. Methodology/Principal Findings: We randomly selected 145 cHL patients with formalin-fixed, paraffin embedded tissue blocks available from 5 hospitals from the Northern part of China. Hematoxylin & Eosin-stained slides were used to reclassify the histological subtypes according to the WHO classification....
Xin Huang, Anke van den Berg, Zifen Gao, Lydia Visser, Ilja Nolte, Hans Vos, Bouke Hepkema, Wierd Kooistra, Sibrand Poppema, Arjan Diepstra