Anke van den Berg
prof. dr.
I work as a clinical molecular biologist in the department of Pathology. In this function I supervise and implement advanced molecular diagnostic techniques. Within my research line, I focus on the molecular pathogenesis of B-cell Hodgkin and non-Hodgkin lymphoma. The specific fields of interest are genomic aberrations, genetic susceptibility, and the role of small and long noncoding RNAs. I have several international collaborations and am PI and co-PI in various projects.
Induction of glomerular alkaline phosphatase after challenge with lipopolysaccharide
Published in: International Journal of Experimental Pathology
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10.1046/j.1365-2613.2003.00345.x
Alkaline phosphatase (AP) can be considered as a host defence molecule since this enzyme is able to detoxify bacterial endotoxin at physiological pH. The question emerged whether this anti-endotoxin principle is inducible in the glomerulus and if so, which glomerular cells might be involved in the expression of ectoAP after stimulation with pro-inflammatory agents. Therefore kidneys of rats treated with either lipopolysaccharide (LPS), E. coli bacteria or non-toxic monophosphoryl lipid A (MPLA) were examined for AP activity 6 or 24 h after challenge. In addition cultures of endothelial...
Jola Jovita Kapojos, Klaas Poelstra, Theo Borghuis, Anke van den Berg, Hans J. Baelde, P.A Klok, W.W Bakker
High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma
Published in: Genes Chromosomes & Cancer
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10.1002/gcc.10186
Anke van den Berg, Bart-Jan Kroesen, K. Kooistra, Doetje de Jong, J. Briggs, T. Blokzijl, S. Jacobs, J. Kluiver, Arjan Diepstra, Ewerton Maggio, Sibrand Poppema
FAS gene mutation in a case of autoimmune lymphoproliferative syndrome type IA with accumulation of gamma delta+ T cells
Anke van den Berg, R. Tamminga, Doetje de Jong, Ewerton Maggio, W.A. Kamps, Sibrand Poppema
Follicular lymphoma grade 3B includes 3 cytogenetically defined subgroups with primary t(14;18), 3q27, or other translocations: t(14;18) and 3q27 are mutually exclusive
Published in: Blood
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10.1182/blood.V101.3.1149
A.G. Bosga-Bouwer, G.W. van Imhoff, Ronald Boonstra, A. van der Veen, E. Haralambieva, Anke van den Berg, B. de Jong, V. Krause, M.C. Palmer, R. Coupland, P.M. Kluin, Eva van den Berg, Sibrand Poppema
Low frequency of FAS mutations in Reed-Sternberg cells of Hodgkin’s lymphoma
Ewerton Maggio, Anke van den Berg, Doetje de Jong, Arjan Diepstra, Sibrand Poppema