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Anke van den Berg
prof. dr.

I work as a clinical molecular biologist in the department of Pathology. In this function I supervise and implement advanced molecular diagnostic techniques. Within my research line, I focus on the molecular pathogenesis of B-cell Hodgkin and non-Hodgkin lymphoma. The specific fields of interest are genomic aberrations, genetic susceptibility, and the role of small and long noncoding RNAs. I have several international collaborations and am PI and co-PI in various projects.

Lung cancer and COPD: Overlapping origins of disease?
Mirjam Boelens, Anke van den Berg, Gerard te Meerman, Rudolf Fehrmann, Wouter de Jong, Marie Geerlings, Wim Timens, Dirkje Postma, Harry Groen
Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma
Published in: HEMATOLOGICAL ONCOLOGY
To identify genes involved in the pathogenesis of classical Hodgkin lymphoma (cHL), we performed serial analysis of gene expression (SAGE) and array-based comparative genomic hybridization (aCGH). Comparison of SAGE libraries of cHL cell lines L428 and L1236 with that of germinal centre B cells revealed consistent overexpression of only 14 genes. In contrast, 141 genes were downregulated in both cHL cell lines, including many B cell and HLA genes. aCGH revealed gain of 2p, 7p, 9p, 11q and Xq and loss of 4q and 11q. Eighteen percent of...
Joost Kluiver, Klaas Kok, Ines Pfeil, Debora de Jong, Tjasso Blokzijl, Geert Harms, Pieter van der Vlies, Arjan Diepstra, Cigdem Atayar, Sibrand Poppema, Ralf Kueppers, Anke van den Berg
Cytokines, cytokine receptors and chemokines in Hodgkin lymphoma.
5 ‘-UTR FAS mutation pattern and frequency in nodal diffuse large B-cell lymphoma similar to normal germinal center B cells
Published in: Leukemia and Lymphoma
Deletion of C-MYC in the spectrum of transformed follicular lymphoma grade 3B: reply
Published in: Human Pathology
Anneke Bosga - Bouwer, Eva van den Berg, Philip Kluin, Sibrand Poppema, Anke van den Berg