Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Can Sequential F-18-FDG PET/CT Replace WBC Imaging in the Diabetic Foot?
Published in: Journal of Nuclear Medicine
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10.2967/jnumed.110.082222
White blood cell (WBC) scintigraphy is considered the nuclear medicine imaging gold standard for diagnosing osteomyelitis in the diabetic foot. Recent papers have suggested that the use of F-18-FDG PET/CT produces similar diagnostic accuracy, but clear interpretation criteria have not yet been established. Our aim was to evaluate the role of sequential F-18-FDG PET/CT in patients with a high suspicion of osteomyelitis to define objective interpretation criteria to be compared with WBC scintigraphy. Methods: Thirteen patients whom clinicians considered positive for osteomyelitis (7 with ulcers, 6 with exposed...
Demetrio Familiari, Andor W. J. M. Glaudemans, Valeria Vitale, Daniela Prosperi, Oreste Bagni, Andrea Lenza, Marco Cavallini, Francesco Scopinaro, Alberto Signore
Myocardial perfusion reserve compared with peripheral perfusion reserve: A [13N]ammonia PET study
Published in: Journal of Nuclear Cardiology
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10.1007/s12350-011-9339-2
INTRODUCTION: [13N]ammonia PET allows quantification of myocardial perfusion. The similarity between peripheral flow and myocardial perfusion is unclear. We compared perfusion flow in the myocardium with the upper limb during rest and adenosine stress [13N]ammonia PET to establish whether peripheral perfusion reserve (PPR) correlates with MPR. METHODS: [13N]ammonia myocardial perfusion PET-scans of 58 patients were evaluated (27 men, 31 women, age 64 ± 13 years) and were divided in four subgroups: patients with coronary artery disease (CAD, n = 15), cardiac syndrome X (SX, n = 14), idiopathic...
A. M. Scholtens, R. A. Tio, A. Willemsen, R. A. J. O. Dierckx, Hendrikus Boersma, C. J. Zeebregts, A. W. J. M. Glaudemans, R. H. J. A. Slart
Infection imaging using SPECT-CT
Published in: Atlas of SPECT-CT imaging
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10.1007/978-3-642-15726-4_9
Onelio Geatti, Andor W.J.M. Glaudemans, Elena Lazzeri, Alberto Signore
Whole body amyloid deposition imaging by 123I-SAP scintigraphy
Amyloidosis is the name of a group of diseases characterized by extracellular deposition of amyloid fibrils. Deposition of amyloid can be localized or systemic. The 123I-SAP-scan can be used to image extent and distribution of amyloid deposition in patients with systemic AA, AL and ATTR amyloidosis. Images are assessed in a semi-quantitative way by comparing each organ directly or indirectly to the normal blood-pool distribution. Considerable variation is observed between the findings on 123I-SAP-scan and clinical manifestations of organ disease. Regardless, the 123I-SAP-scan still provides both an impression...
Ronald van Rheenen, Andor Glaudemans, Bouke Hazenberg
Radionuclide imaging of bone marrow disorders
Published in: European Journal of Nuclear Medicine and Molecular Imaging
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10.1007/s00259-010-1531-0
document
Noninvasive imaging techniques have been used in the past for visualization the functional activity of the bone marrow compartment. Imaging with radiolabelled compounds may allow different bone marrow disorders to be distinguished. These imaging techniques, almost all of which use radionuclide-labelled tracers, such as (99m)Tc-nanocolloid, (99m)Tc-sulphur colloid, (111)In-chloride, and radiolabelled white blood cells, have been used in nuclear medicine for several decades. With these techniques three separate compartments can be recognized including the reticuloendothelial system, the erythroid compartment and the myeloid compartment. Recent developments in research and the...