Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
[18F]-Sodium Fluoride Uptake in Takayasu Arteritis
Erick Alexanderson, Andrea De Guadalupe Monroy Gonzalez, L. Juarez-Orozco, R. Tio, A. W. J. M. Glaudemans, Alejandro Estrada-Cuzcano, O. Garcia-Vuelta, A. Meave, R. H. J. A. Slart, M E Soto-Lopez
The added value of 18F-FDG PET for the staging of patients with invasive fungal infections
A. O. Ankrah, A. W. J. M. Glaudemans, E. F. J. de Vries, R. H. J. A. Slart, R. A. J. O. Dierckx, M. M. Sathekge, H. C. Klein
Positron emission tomography of tumour [F-18] fluoroestradiol uptake in patients with acquired hormone-resistant metastatic breast cancer prior to oestradiol therapy
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document
10.1007/s00259-015-3107-5
document
Purpose Whereas anti-oestrogen therapy is widely applied to treat oestrogen receptor (ER) positive breast cancer, paradoxically, oestrogens can also induce tumour regression. Upregulation of ER expression is a marker for oestrogen hypersensitivity. We, therefore, performed an exploratory study to evaluate positron emission tomography (PET) with the tracer 16 alpha-[F-18] fluoro-17 beta-oestradiol (F-18-FES) as potential marker to select breast cancer patients for oestradiol therapy. Methods Eligible patients had acquired endocrine-resistant metastatic breast cancer that progressed after >= 2 lines of endocrine therapy. All patients had prior ER-positive histology. Treatment...
Michel van Kruchten, Andor W. J. M. Glaudemans, Erik F. J. de Vries, Carolien P. Schröder, Elisabeth G. E. de Vries, Geke A. P. Hospers
Insulinoma Manifesting Early Postpartum: Case Report and Review of the Literature
Published in: AACE Clinical Case Reports
Access to document
10.4158/EP14549.CR
document
Objective: Insulinomas are insulin-producing neuroendocrine tumors. Insulinomas presenting during pregnancy and the early postpartum period are very rare. Methods: A 33-year-old woman with hypoglycemia early postpartum is described. Abdominal computed tomography and endoscopic ultrasound showed 2 lesions of the pancreas. An 11C-5-hydroxy-L-tryptophan (11CHTP) positron emission tomography-computed tomography (PET-CT) scan demonstrated additional uptake in lymph nodes and liver, suggesting malignant insulinoma. Six months after pylorus-preserving pancreatoduodenectomy and excision of liver and lymph node metastases, tumor progression was noted on repeated 11C-HTP PET-CT scans without recurrent hypoglycemia. She was enrolled...
Eske Christiane Gertje, Annemiek M.E. Walenkamp, Andor W.J.M. Glaudemans, Sander A.J.C. IJtsma, Klaas Hoogenberg, Robin P.F. Dullaart
Different Scoring Methods of FDG PET/CT in Giant Cell Arteritis: Need for Standardization
Published in: Medicine
Access to document
10.1097/MD.0000000000001542
document
Giant cell arteritis (GCA) is the most frequent form of vasculitis in persons older than 50 years. Cranial and systemic large vessels can be involved. [F-18] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is increasingly used to diagnose inflammation of the large arteries in GCA. Unfortunately, no consensus exists on the preferred scoring method. In the present study, we aim to define the optimal FDG PET/CT scoring method for GCA diagnosis using temporal artery biopsy and clinical diagnosis as the reference method. FDG PET/CT scans of GCA...
Menno D. Stellingwerff, Elisabeth Brouwer, Karel-Jan D. F. Lensen, Abraham Rutgers, Suzanne Arends, Kornelis S. M. van der Geest, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart