Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Pharmacodynamic analysis from a phase 1 study of rintodestrant (G1T48), an oral selective estrogen receptor degrader, in ER+/HER2-locally advanced or metastatic breast cancer
Philippe Aftimos, Marina Maglakelidze, Andor W. J. M. Glaudemans, Erika Hamilton, Linnea Chap, Elisabeth de Vries, Catharina Willemien Menke-van der Houven van Oordt, Agnes Jager, E. Claire Dees, Massimo Cristofanilli, Mark Pegram, Susanna Ulahannan, Patrick Neven, Iurie Bulat, Ruhi Rai, Wenli Tao, Sarika Jain, Andrew P. Beelen, Jessica A. Sorrentino
PET/CT Imaging for Personalized Management of Infectious Diseases
Published in: Journal of personalized medicine
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10.3390/jpm11020133
document
Serial [F-18]-FDHT-PET to predict bicalutamide efficacy in patients with androgen receptor positive metastatic breast cancer
Published in: European Journal of Cancer
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10.1016/j.ejca.2020.11.008
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Background: The androgen receptor (AR) is a potential target in metastatic breast cancer (MBC), and 16 beta-[F-18]-fluoro-5 alpha-dihydrotestosterone positron emission tomography ([F-18]-FDHT-PET) can be used for noninvasive visualisation of AR. [F-18]-FDHT uptake reduction during AR-targeting therapy reflects AR occupancy and might be predictive for treatment response. We assessed the feasibility of [F-18]-FDHT-PET to detect changes in AR availability during bicalutamide treatment and correlated these changes with treatment response. Patients and methods: Patients with AR thorn MBC, regardless of oestrogen receptor status, received an [F-18]-FDHT-PET at baseline and after...
Jorianne Boers, Clasina M Venema, Erik F J de Vries, Geke A P Hospers, Hendrikus H Boersma, Bart Rikhof, Christine Dorbritz, Andor W J M Glaudemans, Carolina P Schröder
Assessment of Bone Lesions with F-18-FDG PET Compared with Tc-99m Bone Scintigraphy Leads to Clinically Relevant Differences in Metastatic Breast Cancer Management
Published in: Journal of Nuclear Medicine
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10.2967/jnumed.120.244640
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It is unknown whether assessment of potential bone lesions in metastatic breast cancer (MBC) by F-18-FDG PET instead of Tc-99m bone scintigraphy (BS) supports clinically relevant changes in MBC management. Therefore, we retrospectively compared management recommendations based on bone lesion assessment by (18)FFDG PET plus contrast-enhanced CT (ceCT) or BS plus ceCT, for patients with newly diagnosed MBC. Methods: Baseline ceCT, BS, and F-18-FDG PET for all patients included in the IMPACT-MBC study (NCT01957332) at the University Medical Center Groningen were reviewed for bone lesions. If bone lesions...
Suzanne C van Es, Ton Velleman, Sjoerd G Elias, Frederike Bensch, Adrienne H Brouwers, Andor W J M Glaudemans, Thomas C Kwee, Marleen Woltman-van Iersel, John H Maduro, Sjoukje F Oosting, Elisabeth G E de Vries, Carolina P Schröder
The Added Value of [18F]FDG PET/CT in the Management of Invasive Fungal Infections
Published in: Diagnostics
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10.3390/diagnostics11010137
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Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented...
Alfred O Ankrah, Dina Creemers-Schild, Bart de Keizer, Hans C Klein, Rudi A J O Dierckx, Thomas C Kwee, Lambert F R Span, Pim A de Jong, Mike M Sathekge, Andor W J M Glaudemans