Skip to main content
Andor Glaudemans
prof. dr.

I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.

Kinetics and 28-day test-retest repeatability and reproducibility of [C-11]UCB-J PET brain imaging
Published in: Journal of Cerebral Blood Flow and Metabolism
Access to document 10.1177/0271678X20964248 document
[C-11]UCB-J is a novel radioligand that binds to synaptic vesicle glycoprotein 2A (SV2A). The main objective of this study was to determine the 28-day test-retest repeatability (TRT) of quantitative [C-11]UCB-J brain positron emission tomography (PET) imaging in Alzheimer’s disease (AD) patients and healthy controls (HCs). Nine HCs and eight AD patients underwent two 60 min dynamic [C-11]UCB-J PET scans with arterial sampling with an interval of 28 days. The optimal tracer kinetic model was assessed using the Akaike criteria (AIC). Micro-/macro-parameters such as tracer delivery (K-1) and volume...
Hayel Tuncel, Ronald Boellaard, Emma M Coomans, Erik FJ de Vries, Andor WJM Glaudemans, Paula Kopschina Feltes, David V García, Sander CJ Verfaillie, Emma E Wolters, Steven P Sweeney, J Michael Ryan, Magnus Ivarsson, Berkley A Lynch, Patrick Schober, Philip Scheltens, Robert C Schuit, Albert D Windhorst, Peter P De Deyn, Bart NM van Berckel, Sandeep SV Golla
Position paper of the EACVI and EANM on artificial intelligence applications in multimodality cardiovascular imaging using SPECT/CT, PET/CT, and cardiac CT
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-021-05341-z document
In daily clinical practice, clinicians integrate available data to ascertain the diagnostic and prognostic probability of a disease or clinical outcome for their patients. For patients with suspected or known cardiovascular disease, several anatomical and functional imaging techniques are commonly performed to aid this endeavor, including coronary computed tomography angiography (CCTA) and nuclear cardiology imaging. Continuous improvement in positron emission tomography (PET), single-photon emission computed tomography (SPECT), and CT hardware and software has resulted in improved diagnostic performance and wide implementation of these imaging techniques in daily clinical...
Riemer H J A Slart, Michelle C Williams, Luis Eduardo Juarez-Orozco, Christoph Rischpler, Marc R Dweck, Andor W J M Glaudemans, Alessia Gimelli, Panagiotis Georgoulias, Olivier Gheysens, Oliver Gaemperli, Gilbert Habib, Roland Hustinx, Bernard Cosyns, Hein J Verberne, Fabien Hyafil, Paola A Erba, Mark Lubberink, Piotr Slomka, Ivana Išgum, Dimitris VisvikisMárton Kolossváry, Antti Saraste
Clinical implications of increased uptake in bone marrow and spleen on FDG-PET in patients with bacteremia
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-020-05071-8 document
PURPOSE: To investigate which clinical factors and laboratory values are associated with high FDG uptake in the bone marrow and spleen on 2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) in patients with bacteremia. METHODS: One hundred forty-five consecutive retrospective patients with bacteremia who underwent FDG-PET/CT between 2010 and 2017 were included. Mean standard uptake values (SUVmean) of FDG in bone marrow, liver, and spleen were measured. Bone marrow-to-liver SUV ratios (BLR) and spleen-to-liver SUV ratios (SLR) were calculated. Linear regression analyses were performed to examine the association...
Jordy P. Pijl, Thomas C. Kwee, Riemer H. J. A. Slart, Derya Yakar, Marjan Wouthuyzen-Bakker, Andor W. J. M. Glaudemans
FDG-PET/CT in intensive care patients with bloodstream infection
Published in: Critical care (London, England)
Access to document 10.1186/s13054-021-03557-x document
BACKGROUND: 2-Deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) is an advanced imaging technique that can be used to examine the whole body for an infection focus in a single examination in patients with bloodstream infection (BSI) of unknown origin. However, literature on the use of this technique in intensive care patients is scarce. The purpose of this study was to evaluate the diagnostic yield of FDG-PET/CT in intensive care patients with BSI. METHODS: In this retrospective cohort study, all intensive care patients from our Dutch university medical...
Jordy P Pijl, Mark Londema, Thomas C Kwee, Maarten W N Nijsten, Riemer H J A Slart, Rudi A J O Dierckx, Peter H J van der Voort, Andor W J M Glaudemans, Janesh Pillay
Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular diseases: a joint collaboration of the EACVI and the EANM
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-020-05066-5 document
With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is). This standard should be applied in clinical practice and integrated in clinical (multicenter) trials for optimal procedural standardization. A major focus is put on procedures using [18F]FDG, but 4Is PET radiopharmaceuticals beyond [18F]FDG are also described in this document. Whilst these novel tracers are currently mainly applied in early clinical trials, some multicenter trials are underway and we foresee in the near...
4Is Cardiovascular Imaging: a joint initiative of the European Association of Cardiovascular Imaging (EACVI), Riemer H J A Slart, Andor W J M Glaudemans, Olivier Gheysens, Mark Lubberink, Tanja Kero, Marc R Dweck, Gilbert Habib, Oliver Gaemperli, Antti Saraste, Alessia Gimelli, Panagiotis Georgoulias, Hein J Verberne, Jan Bucerius, Christoph Rischpler, Fabien Hyafil, Paola A Erba