Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Technical and clinical applications of long-axial-field-of-view/Total Body PET-CT
Perspectives on joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards for [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors
Published in: Cancer imaging
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10.1186/s40644-022-00512-z
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Response assessment in the context of immunomodulatory treatments represents a major challenge for the medical imaging community and requires a multidisciplinary approach with involvement of oncologists, radiologists, and nuclear medicine specialists. There is evolving evidence that [18F]FDG PET/CT is a useful diagnostic modality for this purpose. The clinical indications for, and the principal aspects of its standardization in this context have been detailed in the recently published “Joint EANM/SNMMI/ANZSNM practice guidelines/procedure standards on recommended use of [18F]FDG PET/CT imaging during immunomodulatory treatments in patients with solid tumors version...
E. Lopci, N. Aide, A. Dimitrakopoulou-Strauss, L. Dercle, A. Iravani, R. D. Seban, C. Sachpekidis, O. Humbert, O. Gheysens, A. W.J.M. Glaudemans, W. A. Weber, A. D. Van den Abbeele, R. L. Wahl, A. M. Scott, N. Pandit-Taskar, R. J. Hicks
Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
Published in: Cancer imaging
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10.1186/s40644-022-00507-w
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This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which are characterized by ultra-high sensitivity. This review not only provides an overview of the published clinical applications using LAFOV PET so far, but also provides insight in clinical applications that are currently under investigation. Apart from the straightforward reduction in acquisition times or administered amount of radiotracer, LAFOV...
Joyce van Sluis, Ronald Borra, Charalampos Tsoumpas, Johannes H. van Snick, Mostafa Roya, Dik ten Hove, Adrienne H. Brouwers, Adriaan A. Lammertsma, Walter Noordzij, Rudi A.J.O. Dierckx, Riemer H.J.A. Slart, Andor W.J.M. Glaudemans
Shortened duration whole body 18F-FDG PET Patlak imaging on the Biograph Vision Quadra PET/CT using a population-averaged input function
Published in: EJNMMI physics
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10.1186/s40658-022-00504-9
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Background: Excellent performance characteristics of the Vision Quadra PET/CT, e.g. a substantial increase in sensitivity, allow for precise measurements of image-derived input functions (IDIF) and tissue time activity curves. Previously we have proposed a method for a reduced 30 min (as opposed to 60 min) whole body 18F-FDG Patlak PET imaging procedure using a previously published population-averaged input function (PIF) scaled to IDIF values at 30–60 min post-injection (p.i.). The aim of the present study was to apply this method using the Vision Quadra PET/CT, including the use of a PIF...
Joyce van Sluis, Johannes H. van Snick, Adrienne H. Brouwers, Walter Noordzij, Rudi A.J.O. Dierckx, Ronald J.H. Borra, Adriaan A. Lammertsma, Andor W.J.M. Glaudemans, Riemer H.J.A. Slart, Maqsood Yaqub, Charalampos Tsoumpas, Ronald Boellaard
A Case of Clinical Uncertainty Solved: Giant Cell Arteritis with Polymyalgia Rheumatica Swiftly Diagnosed with Long Axial Field of View PET
Published in: Diagnostics
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10.3390/diagnostics12112694
document
The clinical presentation of giant cell arteritis (GCA) is often nonspecific. Differentiating GCA from infectious, malignant, or other autoimmune pathology based on signs, symptoms, and laboratory parameters may therefore be difficult. Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging is an established tool in the diagnostic workup of GCA. An advantage of 18F-FDG-PET/CT is its ability to assist in the differential diagnosis by being able to demonstrate infection, inflammation, and malignancy when used in conjunction with clinical and laboratory data. Downsides to the use of 18F-FDG-PET/CT include its...
Pieter H. Nienhuis, Joyce van Sluis, Johannes H. van Snick, Andor W.J.M. Glaudemans, Sofie Meijering, Elisabeth Brouwer, Riemer H.J.A. Slart