Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
EANM consensus document on the use of [18F]FDG PET/CT in fever and inflammation of unknown origin
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document
10.1007/s00259-024-06732-8
document
PURPOSE: Patients with fever and inflammation of unknown origin (FUO/IUO) are clinically challenging due to variable clinical presentations with nonspecific symptoms and many differential diagnoses. Positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[ 18F]fluoro-D-glucose ([ 18F]FDG) is increasingly used in FUO and IUO, but the optimal diagnostic strategy remains controversial. This consensus document aims to assist clinicians and nuclear medicine specialists in the appropriate use of [ 18F]FDG-PET/CT in FUO and IUO based on current evidence. METHODS: A working group created by the EANM infection and inflammation committee performed...
Søren Hess, Edel Noriega-Álvarez, Lucia Leccisotti, Giorgio Treglia, Domenico Albano, Anne Roivainen, Andor W J M Glaudemans, Olivier Gheysens
Salivary gland 18F-FDG-PET/CT uptake patterns in Sjögren’s syndrome and giant cell arteritis patients
Published in: Clinical and Experimental Rheumatology
Access to document
10.55563/clinexprheumatol/8qt9me
document
OBJECTIVES: Wide variety in salivary gland 18F-FDG-uptake is observed in the general population. A general consensus about the usefulness of 18F-FDG-PET/CT to detect salivary gland inflammatory conditions, such as in primary Sjögren’s syndrome (pSS), is not yet clear. This study aimed to investigate whether there are differences in uptake of 18F-FDG in salivary glands among two autoimmune groups [pSS, giant cell arteritis (GCA)] and a non-autoimmune group (lung cancer). METHODS: PSS patients aged ≥50 years who underwent 18F-FDG-PET/CT were included and age-matched with GCA patients and a non-autoimmune...
Rob G J Grootelaar, Martha S van Ginkel, Pieter H Nienhuis, Suzanne Arends, Remge M Pieterman, Elisabeth Brouwer, Hendrika Bootsma, Andor W J M Glaudemans, Riemer H J A Slart
The clinical value of quantitative cardiovascular molecular imaging: a step towards precision medicine
Published in: British journal of radiology
Access to document
10.1259/bjr.20230704
document
Cardiovascular diseases (CVD) are the leading cause of death worldwide and have an increasing impact on society. Precision medicine, in which optimal care is identified for an individual or a group of individuals rather than for the average population, might provide significant health benefits for this patient group and decrease CVD morbidity and mortality. Molecular imaging provides the opportunity to assess biological processes in individuals in addition to anatomical context provided by other imaging modalities and could prove to be essential in the implementation of precision medicine in...
Practice of 18F-FDG-PET/CT in ICU Patients: A Systematic Review
Published in: Seminars in Nuclear Medicine
Access to document
10.1053/j.semnuclmed.2023.05.003
document
18F-FDG-PET/CT imaging has become a key tool to evaluate infectious and inflammatory diseases. However, application of 18F-FDG-PET/CT in patients in the intensive care unit (ICU) is limited, which is remarkable since the development of critical illness is closely linked to infection and inflammation. This limited use is caused by perceived complexity and risk of planning and executing 18F-FDG-PET/CT in such patients. The aim of this systematic review was to investigate the feasibility of 18F-FDG-PET/CT in ICU patients with special emphasis on patient preparation, transport logistics and safety. Therefore,...
Long Versus Short Axial Field of View Immuno-PET/CT: Semiquantitative Evaluation for 89Zr-Trastuzumab
Published in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Access to document
10.2967/jnumed.123.265621
document
The purpose of this study was to quantify any differences between the SUVs of 89Zr immuno-PET scans obtained using a PET/CT system with a long axial field of view (LAFOV; Biograph Vision Quadra) compared to a PET/CT system with a short axial field of view (SAFOV; Biograph Vision) and to evaluate how LAFOV PET scan duration affects image noise and SUV metrics. Methods: Five metastatic breast cancer patients were scanned consecutively on SAFOV and LAFOV PET/CT scanners. Four additional patients were scanned using only LAFOV PET/CT. Scans on...
Philipp Mohr, Joyce van Sluis, Laura Providência, Johannes H van Snick, Marjolijn N Lub-de Hooge, Antoon T Willemsen, Andor W J M Glaudemans, Ronald Boellaard, Adriaan A Lammertsma, Adrienne H Brouwers, Charalampos Tsoumpas