Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Current and Emerging Radiotracers in Molecular Cardiovascular Imaging
Published in: Circulation-Cardiovascular Imaging
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10.1161/CIRCIMAGING.123.016323
document
Cardiovascular imaging has rapidly advanced over the past decades. Traditional imaging techniques such as echocardiography, computed tomography, and cardiovascular magnetic resonance are essential for assessing the structural and functional aspects of the cardiovascular system but often fall short in providing direct insights into disease activity. This gap is increasingly being bridged by molecular nuclear imaging techniques, including positron emission tomography and single-photon emission computed tomography, which enable the visualization of disease processes at the molecular and cellular levels. This review highlights the role of cardiovascular molecular imaging, emphasizing...
Shruti S Joshi, Jolien Geers, Alessia Gimelli, Fabien Hyafil, Gilbert Habib, Paola Erba, Olivier Gheysens, Andor W J M Glaudemans, David E Newby, Riemer H J A Slart, Marc R Dweck
EANM/SNMMI guideline/procedure standard for [ 18F]FDG hybrid PET use in infection and inflammation in adults v2.0.
Published in: European Journal of Nuclear Medicine and Molecular Imaging
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10.1007/s00259-024-06915-3
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INTRODUCTION: Hybrid [ 18F]FDG PET imaging is currently the method of choice for a wide variety of infectious and inflammatory disorders and was recently adopted in several clinical guidelines. A large amount of evidence-based articles, guidelines and appropriate use criteria have been published since the first version of this guideline in 2013. PURPOSE: To provide updated evidence-based information to assist physicians in recommending, performing and interpreting hybrid [ 18F]FDG PET examinations for infectious and inflammatory disorders in the adult population. METHODS: A systematic literature search of evidence-based articles...
Gad Abikhzer, Giorgio Treglia, Matthieu Pelletier-Galarneau, John Buscombe, Arturo Chiti, Elizabeth H Dibble, Andor W J M Glaudemans, Christopher J Palestro, Mike Sathekge, Alberto Signore, Francois Jamar, Ora Israel, Olivier Gheysens
Ultrashort Oncologic Whole-Body [18F]FDG Patlak Imaging Using LAFOV PET.
Published in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
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10.2967/jnumed.124.267784
Methods to shorten [ 18F]FDG Patlak PET imaging procedures ranging from 65-90 to 20-30 min after injection, using a population-averaged input function (PIF) scaled to patient-specific image-derived input function (IDIF) values, were recently evaluated. The aim of the present study was to explore the feasibility of ultrashort 10-min [ 18F]FDG Patlak imaging at 55-65 min after injection using a PIF combined with direct Patlak reconstructions to provide reliable quantitative accuracy of lung tumor uptake, compared with a full-duration 65-min acquisition using an IDIF. Methods: Patients underwent a 65-min dynamic PET...
[15O]H2O PET: Potential or Essential for Molecular Imaging?
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2023.08.002
document
Imaging water pathways in the human body provides an excellent way of measuring accurately the blood flow directed to different organs. This makes it a powerful diagnostic tool for a wide range of diseases that are related to perfusion and oxygenation. Although water PET has a long history, its true potential has not made it into regular clinical practice. The article highlights the potential of water PET in molecular imaging and suggests its prospective role in becoming an essential tool for the 21st century precision medicine in different...
Riemer H J A Slart, T Samara Martinez-Lucio, Hendrikus H Boersma, Ronald H Borra, Bart Cornelissen, Rudi A J O Dierckx, Magdalena Dobrolinska, Janine Doorduin, Paola A Erba, Andor W J M Glaudemans, Bruno Lima Giacobbo, Gert Luurtsema, Walter Noordzij, Joyce van Sluis, Charalampos Tsoumpas, Adriaan A Lammertsma
Advances in PET Imaging of Large Vessel Vasculitis: An Update and Future Trends
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2024.03.001
document
Systemic vasculitides are autoimmune diseases characterized by inflammation of blood vessels. They are categorized based on the size of the preferentially affected blood vessels: large-, medium-, and small-vessel vasculitides. The main forms of large-vessel vasculitis include giant cell arteritis (GCA) and Takayasu arteritis (TAK). Depending on the location of the affected vessels, various imaging modalities can be employed for diagnosis of large vessel vasculitis: ultrasonography (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and [ 18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). These imaging tools offer complementary information...
Kornelis S M van der Geest, Olivier Gheysens, Lars C Gormsen, Andor W J M Glaudemans, Charalampos Tsoumpas, Elisabeth Brouwer, Pieter H Nienhuis, Gijs D van Praagh, Riemer H J A Slart