Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
PET/CT in Inflammatory and Auto-immune Disorders: Focus on Several Key Molecular Concepts, FDG, and Radiolabeled Probe Perspectives
Published in: Seminars in Nuclear Medicine
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10.1053/j.semnuclmed.2023.10.005
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Chronic immune diseases mainly include autoimmune and inflammatory diseases. Managing chronic inflammatory and autoimmune diseases has become a significant public health concern, and therapeutic advancements over the past 50 years have been substantial. As therapeutic tools continue to multiply, the challenge now lies in providing each patient with personalized care tailored to the specifics of their condition, ushering in the era of personalized medicine. Precise and holistic imaging is essential in this context to comprehensively map the inflammatory processes in each patient, identify prognostic factors, and monitor treatment...
Florent L Besson, Gaetane Nocturne, Nicolas Noël, Olivier Gheysens, Riemer H J A Slart, Andor W J M Glaudemans
Multimodality imaging to assess diagnosis and evaluate complications of large vessel arteritis
Published in: Journal of Nuclear Cardiology
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10.1016/j.nuclcard.2024.101864
document
Different types of vasculitis can be distinguished according to the blood vessel’s size that is preferentially affected: large-vessel, medium-vessel, and small-vessel vasculitides. Giant cell arteritis (GCA) and Takayasu’s arteritis (TAK) are the main forms of large-vessel vasculitis, and may lead to lumen narrowing. Clinical manifestations of arterial narrowing on the short- and long term include vision loss, stroke, limb ischaemia and heart failure. Imaging tools are well established diagnostic tests for large-vessel vasculitis and may aid therapy monitoring in selected cases, while providing important information regarding the occurrence...
Ayaz Aghayev, Britanny Weber, Tiago Lins de Carvalho, Andor W J M Glaudemans, Pieter H Nienhuis, Kornelis S M van der Geest, Riemer H J A Slart
[18F]FDG PET/CT imaging of spinal infections
Published in: Clinical and Translational Imaging
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10.1007/s40336-024-00629-0
document
The annual incidence of spinal infections has been rising significantly over the last years and is expected to increase even further. Spinal infections may include infection of the vertebral body and intervertebral disc (spondylodiscitis), paravertebral abscess, epidural abscess and septic arthritis of the facet joints. Positron emission tomography (PET) with [18F]FDG has high sensitivity for detecting spinal infections, may help in differentiating between spinal infection subtypes and is able to detect dissemination of infection outside the spine. [18F]FDG PET/CT is especially indicated if MRI is inconclusive, in patients...
Erik T. te Beek, Marc R.J. ten Broek, Sakar Abdul-Fatah, Andor W.J.M. Glaudemans
Infective Native Aortic Aneurysm: a Delphi Consensus Document on Treatment, Follow Up, and Definition of Cure
Published in: European Journal of Vascular and Endovascular Surgery
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10.1016/j.ejvs.2023.12.008
document
Objective: Evidence is lacking to guide the management of infective native aortic aneurysm (INAA). The aim of this study was to establish expert consensus on surgical and antimicrobial treatment and follow up, and to define when an INAA is considered cured. Methods: Delphi methodology was used. The principal investigators invited 47 international experts (specialists in infectious diseases, radiology, nuclear medicine, and vascular and cardiothoracic surgery) via email. Four Delphi rounds were performed, three weeks each, using an online questionnaire with initially 28 statements. The panellists rated the statements...
the Academic Research Consortium of Infective Native Aortic Aneurysm (ARC of INAA), Thomas R. Wyss, Matteo Giardini, Karl Sörelius, Andor W.J.M. Glaudemans, Riemer H.J.A. Slart
Prevalence of wild-type transthyretin amyloidosis in a prospective heart failure cohort with preserved and mildly reduced ejection fraction: Results of the Amylo-VIP-HF study
Published in: European Journal of Heart Failure
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10.1002/ejhf.3186
document
Alwin Tubben, Hendrea S.A. Tingen, Niek H.J. Prakken, Vanessa P.M. van Empel, Thomas M. Gorter, Laura M.G. Meems, Olivier C. Manintveld, Michiel Rienstra, Robert G. Tieleman, Andor W.J.M. Glaudemans, Dirk J. van Veldhuisen, Riemer H.J.A. Slart, Hans L.A. Nienhuis, Peter van der Meer