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Andor Glaudemans
prof. dr.

I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.

Diagnostic value and interpretability of [ 18F]FDG-PET/CT radiomics in infective endocarditis.
Published in: EJNMMI Research
Access to document 10.1186/s13550-025-01366-9 document
BACKGROUND: to assess the value of [18 F]FDG PET/CT radiomics in infective endocarditis (IE) diagnosis. We evaluated and collected [18 F]FDG PET/CT and clinical data of 447 patients, with suspected IE studied in 3 centers. Radiomic features were calculated and after dimensionality reduction, we performed: (1) univariate testing for assessing the discrimination power of clinical variables and radiomics; (2) a multivariate random forest-based model fed by radiomics to predict the outcome of PET/CT visual analysis; (3) a clustering-based radiomic model to predict final diagnosis; (4) a series of...
Paola Anna Erba, Roberta Zanca, Martina Sollini, Lara Cavinato, Alessandra Ragni, Derk Ten Hove, Andor Wjm Glaudemans, Santiago Aguadè-Bruix, Maria N Pizzi, Albert Roque, Francesca Ieva, Riemer Hja Slart
Clinical evaluation of dynamic [18F]FDG PET imaging to distinguish infection from inflammation in fracture-related infections.
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-025-07563-x document
BACKGROUND: Standard [ 18F]FDG PET/CT is widely used to detect infections, but is limited in differentiating bacterial infection from inflammation due to overlapping uptake patterns. This distinction is particularly challenging in fracture-related infection (FRI), due to multiple factors, including recent surgery, soft tissue injury, fracture healing, and surgical implants. Dynamic [ 18F]FDG imaging over time may overcome this limitation by capturing a rapid, sustained uptake seen in infections, driven by ongoing immune and microbial activity, as opposed to the potentially slower uptake in inflammation. This study investigates the...
N D van Rijsewijk, M Wouthuyzen-Bakker, J H van Snick, J van Sluis, R H J A Slart, A W J M Glaudemans, F F A IJpma
Diagnostic value of [18F]FDG PET/CT for detection of infectious and inflammatory foci in critically ill patients: a systematic review and meta-analysis
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-025-07759-1
Giorgio Treglia, Domenico Albano, Xavier Wittebole, Andor W J M Glaudemans, Janesh Pillay, Olivier Gheysens
Differential [18F]FAPI-42 and [18F]FDG uptake patterns distinguish desmoid tumours from GISTs on PET/CT imaging
Published in: European Journal of Nuclear Medicine and Molecular Imaging
Access to document 10.1007/s00259-025-07707-z
BACKGROUND: Intra-abdominal desmoid tumours (IADT) can closely mimic gastrointestinal stromal tumours (GISTs), particularly in recurrence and metastases. However, differentiating these two diseases using radiological methods remains challenging. This study aimed to investigate the value of [ 18F]FAPI-42 PET/CT in differentiating IADT and GISTs compared to [ 18F]FDG PET/CT. METHODS: This study retrospectively included a total of 24 patients (12 patients with IADT and 12 patients with recurrent/metastatic GISTs) who underwent two separate PET/CT scans using [ 18F]FAPI-42 and [ 18F]FDG, respectively. The differences in tumour SUV max on...
Chunhui Wu, Xiaoyan Wang, Xiaojie Lin, Andor W J M Glaudemans, Bart Cornelissen, Walter Noordzij, Xin Hu, Yu Zeng, Xiangsong Zhang, Xinhua Zhang
2023 European Society of Cardiology guidelines for the management of infective endocarditis: Statement of endorsement by the NVVC Full version
Published in: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Access to document 10.1007/s12471-025-02010-w document
This review evaluates the 2023 European Society of Cardiology (ESC) guidelines for the management of infective endocarditis (IE) and offers insights into topics particularly relevant to clinical practice in the Netherlands. The multidisciplinary IE Working Group assessed all ESC recommendations and concluded that the majority could be endorsed, albeit with certain modifications. The IE Working Group presents a refined (and simplified) antibiotic prophylactic regimen and an updated table to guide the analysis of suspected blood culture-negative IE. Furthermore, the pivotal role of the Endocarditis Team in the management...
Annelot J L Peijster, Cees van Nieuwkoop, Ruud W M Keunen, Susanne Felix, Berend J van Welzen, Ilse J E Kouijzer, C H Edwin Boel, Nelianne J Verkaik, Ka Yan Lam, Robert J M Klautz, Andor W J M Glaudemans, Ricardo P J Budde, Alexander H Maass, Reinoud E Knops, Otto Kamp, Wilco Tanis