Andor Glaudemans
prof. dr.
I am a nuclear medicine specialist and always trying to implement innovative diagnostic and therapeutic methods in imaging. My main research interests involve infectious and inflammatory diseases, tumor-immunology, and development of new-targeted diagnostic tools for PET imaging. The latter focus is carried out in close collaboration with our radiochemists. Within the lymphoma research Groningen team we have a close collaboration with the department of hematology. The research is focused on finding new methods for diagnosis and therapy evaluation in several types of lymphomas. We have a special interest in post-transplant lymphatic disorders (PTLD). Furthermore, we are developing and evaluating several fields of radionuclide therapy, so called theranostics.
Insulinoma Manifesting Early Postpartum: Case Report and Review of the Literature
Published in: AACE Clinical Case Reports
Access to document
10.4158/EP14549.CR
document
Objective: Insulinomas are insulin-producing neuroendocrine tumors. Insulinomas presenting during pregnancy and the early postpartum period are very rare. Methods: A 33-year-old woman with hypoglycemia early postpartum is described. Abdominal computed tomography and endoscopic ultrasound showed 2 lesions of the pancreas. An 11C-5-hydroxy-L-tryptophan (11CHTP) positron emission tomography-computed tomography (PET-CT) scan demonstrated additional uptake in lymph nodes and liver, suggesting malignant insulinoma. Six months after pylorus-preserving pancreatoduodenectomy and excision of liver and lymph node metastases, tumor progression was noted on repeated 11C-HTP PET-CT scans without recurrent hypoglycemia. She was enrolled...
Eske Christiane Gertje, Annemiek M.E. Walenkamp, Andor W.J.M. Glaudemans, Sander A.J.C. IJtsma, Klaas Hoogenberg, Robin P.F. Dullaart
Different Scoring Methods of FDG PET/CT in Giant Cell Arteritis: Need for Standardization
Published in: Medicine
Access to document
10.1097/MD.0000000000001542
document
Giant cell arteritis (GCA) is the most frequent form of vasculitis in persons older than 50 years. Cranial and systemic large vessels can be involved. [F-18] fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is increasingly used to diagnose inflammation of the large arteries in GCA. Unfortunately, no consensus exists on the preferred scoring method. In the present study, we aim to define the optimal FDG PET/CT scoring method for GCA diagnosis using temporal artery biopsy and clinical diagnosis as the reference method. FDG PET/CT scans of GCA...
Menno D. Stellingwerff, Elisabeth Brouwer, Karel-Jan D. F. Lensen, Abraham Rutgers, Suzanne Arends, Kornelis S. M. van der Geest, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart
TGF-beta Antibody Uptake in Recurrent High-Grade Glioma Imaged with Zr-89-Fresolimumab PET
Published in: Journal of Nuclear Medicine
Access to document
10.2967/jnumed.115.154401
Transforming growth factor-beta (TGF-beta) signaling is involved in glioma development. The monoclonal antibody fresolimumab (GC1008) can neutralize all mammalian isoforms of TGF-beta, and tumor uptake can be visualized and quantified with Zr-89-fresolimumab PET in mice. The aim of this study was to investigate the fresolimumab uptake in recurrent high-grade gliomas using Zr-89-fresolimumab PET and to assess treatment outcome in patients with recurrent high-grade glioma treated with fresolimumab. Methods: Patients with recurrent glioma were eligible. After intravenous administration of 37 MBq (5 mg) of Zr-89-fresolimumab, PET scans were acquired...
Martha W. den Hollander, Frederike Bensch, Andor W. J. M. Glaudemans, Thijs H Oude Munnink, Roelien H. Enting, Wilfred F. A. den Dunnen, Mart A. A. M. Heesters, Frank A. E. Kruyt, Marjolijn N. Lub-de Hooge, Jan Cees de Groot, Joseph Pearlberg, Jourik A. Gietema, Elisabeth G. E. de Vries, Annemiek M. E. Walenkamp
18F-FDG-PET-CT assessed subclinical arterial inflammation is positively associated with non-invasive markers of arterial stiffness in recently diagnosed type 2 diabetes patients
S. A. De Boer, Marieke C Hovinga-de Boer, J. D. Lefrandt, A. M. Van Roon, P. W. Kamphuisen, H. L. Lutgers, A. W. J. M. Glaudemans, H. J. Lambers Heersprink, R. H. J. Slart, D. J. Mulder
Nuclear Medicine and Radiologic Imaging in Sports Injuries